Circulating sTREM-1 as a predictive biomarker of pediatric multisystemic inflammatory syndrome (MIS-C)

Gonçalves, Guilherme Salles De Escobar; Correa‐Silva, Simone; Zheng, Yingying; Avelar, Isabela; Montenegro, Marília M.; Ferreira, Arthur E.F.; Bain, Vera; Fink, Thais T.; Suguita, Priscila; Astley, Camilla; Lindoso, Lívia; Martins, Fernanda; Matsuo, Olivia Mari; Ferreira, Juliana Carvalho; Firigato, Isabela; Gonçalves, Fernanda de Toledo; Pereira, Maria Fernanda Bádue; Silva, Clovis Artur A. da; Carneiro‐Sampaio, Magda; Marques, Heloísa Helena de Souza; Palmeira, Patrícia

doi:10.1016/j.cyto.2022.156084

Cytokine

2023

DOI: 10.1016/j.cyto.2022.156084

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Circulating sTREM-1 as a predictive biomarker of pediatric multisystemic inflammatory syndrome (MIS-C)

Guilherme Salles De Escobar Gonçalves

Simone Correa‐Silva

Yingying Zheng

et al.

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2024

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Role of triggering receptor expressed on myeloid cells-1 in kidney diseases: A biomarker and potential therapeutic target

Fan,

Xu,

Huo

et al. 2024

Chinese Medical Journal

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Triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the immunoglobulin superfamily. As an amplifier of the inflammatory response, TREM-1 is mainly involved in the production of inflammatory mediators and the regulation of cell survival. TREM-1 has been studied in infectious diseases and more recently in non-infectious disorders. More and more studies have shown that TREM-1 plays an important pathogenic role in kidney diseases. There is evidence that TREM-1 can not only be used as a biomarker for diagnosis of disease but also as a potential therapeutic target to guide the development of novel therapeutic agents for kidney disease. This review summarized molecular biology of TREM-1 and its signaling pathways as well as immune response in the progress of acute kidney injury, renal fibrosis, diabetic nephropathy, immune nephropathy, and renal cell carcinoma.

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Role of triggering receptor expressed on myeloid cells-1 in kidney diseases: A biomarker and potential therapeutic target

Fan,

Xu,

Huo

et al. 2024

Chinese Medical Journal

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show abstract

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Circulating sTREM-1 as a predictive biomarker of pediatric multisystemic inflammatory syndrome (MIS-C)

Cited by 1 publication

References 52 publications

Role of triggering receptor expressed on myeloid cells-1 in kidney diseases: A biomarker and potential therapeutic target

Role of triggering receptor expressed on myeloid cells-1 in kidney diseases: A biomarker and potential therapeutic target

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