“…10 Paccamonti et al determined plasma concentrations of relaxin in cows with various delivery vehicles and routes of administration by RIA. 11 High sensitivity ($10 pg mL À1 for H2 relaxin) and high sample throughput are the vital virtues of immunoassay. However, the risk of cross-reactivity and the limited linear dynamic ranges, leading to the multiple dilutions of samples, can also compromise the accuracy of quantication.…”
A sensitive analytical method using ultra performance liquid chromatography-tandem mass spectrometry is developed for the determination of recombinant human relaxin-2 (B-29/A-24) in rats for characterizing pharmacokinetics.
“…10 Paccamonti et al determined plasma concentrations of relaxin in cows with various delivery vehicles and routes of administration by RIA. 11 High sensitivity ($10 pg mL À1 for H2 relaxin) and high sample throughput are the vital virtues of immunoassay. However, the risk of cross-reactivity and the limited linear dynamic ranges, leading to the multiple dilutions of samples, can also compromise the accuracy of quantication.…”
A sensitive analytical method using ultra performance liquid chromatography-tandem mass spectrometry is developed for the determination of recombinant human relaxin-2 (B-29/A-24) in rats for characterizing pharmacokinetics.
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