Circulating Cancer Cells

Abstract

Pulmonary Tuberculosis-fohnston et al.BEDICAJ JON,, 1683 46% of the original group. The general acceptability of this regime may well vary in different localities.Since the combination of streptomycin and isoniazid is more effective than P.A.S. + isoniazid it may be possible -to reduce the length of treatment from the generally accepted period of 18 months. We are satisfied that the present results with daily streptomycin + daily isoniazid justify further trials to assess now the optimal duration of these drugs, including possibly an intermittent regime during the later stages of treatment.Conclusions Streptomycin 0.75 g. is an adequate dose and may represent the optimal dose in combination with isoniazid for the treatment of pulmonary tuberculosis.This dose significantly reduces labyrinthine damage. Pantothenic acid has failed to prevent this complication.High

The Selection Strategy for Circulating Tumor Cells (CTCs) Isolation and Enumeration: Technical Features, Methods, and Clinical Applications

“…In 1906, Goldmann reported that visible venous invasion by cancer in approximately 20% of 500 necropsies and microscopic invasion of vasculature in nearly 10% [3]. In very early 1900s, several reports of observation of free cancer cells by morphology have been discussed in patients with melanoma, gastric cancer [4][5][6], and lung cancer [7]. However, long being in the technical limitation on isolation of these rare cells in circulation, the realization of CTCs isolated from living cancer patients and analysis of their clinical impacts began since 1930s [8][9][10].…”

Designing Fractal Nanostructured Biointerfaces for Biomedical Applications

“…There are tremendous and urgent demands to diagnose cancer at an early stage. CTCs79 play a crucial role during the progression of metastasis and have been regarded as an emerging cancer‐related biomarker due to their potential applications in the examination of cancer metastasis, prediction of patient prognosis, and monitoring of the therapeutic outcomes of cancer 80. However, detection of CTCs has been technically challenging due to the extremely low abundance of CTCs among a large number of blood cells (10 9 mL).…”

Circulating cancer cells: The effect of surgical operations

“…The criteria by which cells were assessed for malignancy have been reported previously (Sellwood, Kuper, Burn, and Wallace, 1964) and all samples which contained only one or two doubtful cells were recorded as negative. The numbers of cancer cells in positive samples were recorded in all but 2, in which the preparations had deteriorated by the time of the final assessment.…”