In this paper, we present a novel design of a compact miniaturized dual-band antenna for industrial, scientific, and medical (ISM) implantable applications working at 915 MHz and 2.4 GHz. The proposed antenna has a compact size of (6 × 6 × 0.25 mm 3 ). The antenna shows a wide bandwidth of 12.6 % at the lowest frequency and 12.8 % at the highest frequency and gain values of -21.8 dBi and -19.2 dBi at 915 MHz and 2.4 GHz, respectively which are relatively high for implantable applications. The design has been done for healthy and unhealthy tissues (adenocarcinoma). Furthermore, the fabricated prototype has been tested in minced pork as a suitable real tissue to validate the simulated results. Finally, a comparison with the recently published state-of-the-art solutions is provided showing good results in terms of size, bandwidth and gain.INDEX TERMS Dual band, frequency-independent antenna, implantable antenna, industrial, scientific, and medical (ISM) bands, miniaturization