“…Recently, circRNAs have been described as biomarkers in human saliva and Drosophila . The functions of circRNAs include acting as miRNA sponges and regulating gene expression through a circRNAâmiRNAâmRNA pathway, etc . Increasing studies have demonstrated that circRNAs play a crucial role in various biologic processes such as cell development, proliferation, metastasis, fate decision, migration, and invasion …”