Cinnamon and its possible impact on COVID-19: The viewpoint of traditional and conventional medicine

Abstract

The COVID-19 global epidemic caused by coronavirus has affected the health and other aspects of life for more than one year. Despite the current pharmacotherapies, there is still no specific treatment, and studies are in progress to find a proper therapy with high efficacy and low side effects. In this way, Traditional Persian Medicine (TPM), due to its holistic view, can provide recommendations for the prevention and treatment of new diseases such as COVID-19. The muco-obstruction of the airway, which occurs in SARS-CoV-2, has similar features in TPM textbooks that can lead us to new treatment approaches. Based on TPM and pharmacological studies, Cinnamomum verum (Darchini)'s potential effective functions can contribute to SARS-CoV-2 infection treatment and has been known to be effective in corona disease in Public beliefs. From the viewpoint of TPM theories, Cinnamon can be effective in SARS-CoV-2 improvement and treatment through its anti-obstructive, diuretic, tonic and antidote effects. In addition, there is pharmacological evidence on anti-viral, anti-inflammatory, antioxidant, organ-o-protective and anti-depression effects of Cinnamon that are in line with the therapeutic functions mentioned in TPM. Overall, Cinnamon and its ingredients can be recommended for SARS-CoV2 management due to multi-targeting therapies. This review provides basic information for future studies on this drug's effectiveness in preventing and treating COVID-19 and similar diseases.

An Algerian endemic species in danger to disappear due to pandemic, Origanum vulgare subsp. glandulosum (Desf.) Letsw

“…Glycyrrhiza glabra has an inhibition effect on SARS viral replication and modulates membrane fluidity (Vellingiri et al 2020). Cinnamomum verum has also been demonstrated to have an effect on COVID-19 (Yakhchali et al 2021). Our study showed that G. glabra and C. verum had been used as an infusion of the roots during COVID-19 infection.…”

Investigation of supplement products preferred by healthcare professionals during COVID-19 pandemic process

“…There is also pharmacological evidence for its anti-depressant effects. [25] Green tea-epigallocatechin gallate (EGCG) and black teatheaflavin plants contain copper (Cu), iron (Fe), manganese (Mn), selenium (Se), and zinc (Zn) from the soil. It is recommended for the prophylaxis and treatment of COVID-19 due to the antiviral, antibacterial, immunomodulatory, antioxidant, and anti-inflammatory effects of the polyphenols it contains.…”

Effect of a diet based on Iranian traditional medicine on inflammatory markers and clinical outcomes in COVID-19 patients: A double-blind, randomized, controlled trial

“…However, the aqueous extract demonstrated no marked antiviral function, which implies that the antiviral potential of this herb is mainly contributed to its lipophilic compounds including carotenoids [29] . Saffron and cinnamon have also been well studied for their anti-COVID-19 potential 30 , 31 , 32 . Damask Rose another component of the TPM also used in this study has been evidenced to help the body to excrete the harmful watery phlegm humor highly susceptible to infection and therefore is a tonic of the lungs [10] .…”