“…The morphology of the optic disc varies with its size. The variation in optic disc size is of morphogenetic importance, as eyes with large optic nerve heads, compared with those with small optic nerve heads, have (1) a larger neuroretinal rim area (Jonas et al 1988a), (2) more optic nerve fibers (Quigley et al 1991;Jonas et al 1992), (3) less nerve fiber per mm 2 disc area (Jonas et al 1992), (4) a higher count and a larger total area of lamina cribrosa pores (Jonas et al 1991), (5) a higher ratio of interpore connective tissue area to total lamina cribrosa area (Jonas et al 1991), (6) more cilioretinal arteries (Jonas et al 1988c) and (7) more retinal photoreceptors and retinal pigment epithelium cells in combination with a larger retinal surface area (Panda-Jonas et al 1994).…”