Cigar Use Symposium: Epidemiology, Toxicant Exposure, Health and Policy Implications

Pickworth, Wallace B.; Thanner, Meridith Hill

doi:10.18001/trs.3.2(suppl1).1

Cited by 5 publications

(3 citation statements)

References 7 publications

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“…Cigar smoking research has challenges beyond those associated with cigarette smoking. For example, little cigars are essentially smoked like cigarettesfrom beginning to end, without interruption, and not relighting; whereas cigarillos and large cigars are typically not consumed at one time, they are relit, and they may be chewed or held in the mouth without lighting . Methods developed for cigarette smoking in the laboratory may not be readily applicable to cigar smoking.…”

Section: Discussionmentioning

confidence: 99%

“…The approach extends the results from paradigms that estimate toxicant yield from cigarette smoking based on standardized smoking patterns such as the International Organization for Standardization (ISO) and Federal Trade Commission (FTC). , Although machine smoking of cigarettes has been recognized as not reflective of human smoking, it nevertheless provides a basis for objectively comparing smoke emissions in MSS across a wide range of cigarette products. The wide variations in smoking topography among cigar products complicates the development of a representative machine standard for all cigars. The differences between the various types of cigar products and the use patterns of their consumers have made generalizations about cigar use and their impact on health difficult to establish.…”

Section: Introductionmentioning

confidence: 99%

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Cigarillo and Little Cigar Mainstream Smoke Constituents from Replicated Human Smoking

Pickworth

Rosenberry

et al. 2018

Chem. Res. Toxicol.

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Little cigar and cigarillo smoking is increasing in popularity in the U.S., but little is known about the topography and mainstream smoke (MSS) constituents of these types of cigar products. This report describes the quantity of selected MSS toxicants generated from puff-by-puff replication of human laboratory smoking. Participants were dual users of cigarettes and either little cigars ( n = 21) or cigarillos ( n = 23). In the laboratory smoking session, participants of the little cigar group smoked a filtered unflavored Winchester Little Cigar; those in the cigarillo group smoked an unfiltered, unflavored Black & Mild cigarillo. MSS components included both volatiles and semivolatile compounds. The MSS of five representative U.S. domestic cigarettes was generated using smoking topography profiles of the participants smoking their own brand of cigarettes. Machine smoking accurately replicated individual puff profiles as indicated by a high correlation between lab and machine smoked: time to smoke, number of puffs, and total puff volume. There was wide variability in smoking patterns across subjects of both little cigars and cigarillos. For example, total puff volume ranged from 84 to 732 mL after the little cigar and from 270 to 2089 mL after the cigarillo. Qualitatively, cigar smoke from little cigars and cigarillos were similar and resembles cigarette smoke. All analytes (VOC and SVOCs) were greater in cigarillo smoke compared to that of little cigars and cigarettes. However, when the toxicants were adjusted for grams of tobacco burned, little cigar smoke contained more nicotine, tobacco-specific nitrosamines, acetonitrile, and acrylonitrile compared with cigarillo smoke. When the constituents were adjusted for nicotine content, cigarillo MSS contained more of all toxicants compared with little cigar. Cigarillos and little cigars, like cigarettes, deliver nicotine and other toxicants known to be harmful to health; their regulation by the FDA is appropriate for their public health risk.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cigarillo and Little Cigar Mainstream Smoke Constituents from Replicated Human Smoking

Pickworth

Rosenberry

et al. 2018

Chem. Res. Toxicol.

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“…Even though they are often treated as a class, cigars are a widely diverse group of tobacco products, coming in different lengths, diameters, nicotine content and form, filters, and flavors. − Even the smaller subgroup of little filtered cigar brands investigated in this study were either cherry-flavored, menthol-flavored, or unflavored with tip ventilation ranging from 0.1% to 49%. In addition, their filter design (with or without sepiolite), tobacco rod length (68.5 mm to 73.0 mm), and tobacco rod weight (0.977 to 1.250 g) also varied.…”

Section: Discussionmentioning

confidence: 99%

Mouth Level Intake of Nicotine from Three Brands of Little Filtered Cigars with Widely Differing Product Characteristics Among Adult Consumers

Ashley

Zhu

Watson

et al. 2023

Chem. Res. Toxicol.

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Little filtered cigars are tobacco products with many cigarette-like characteristics. However, despite cigars falling under the U.S. Food and Drug Administration regulatory authority, characterizing flavors, which are still allowed in little filtered cigars, and filter design may influence how people use the products and the resulting exposure to harmful and potentially harmful constituents. We estimated nicotine mouth level intake (MLI) from analyses of little cigar filter butt solanesol levels, brand characteristics, carbon monoxide boost, and puff volume in 48 dual cigarette/cigar users during two repeat bouts of ad lib smoking of three little filtered cigar brands. Mean nicotine MLI for the three brands was significantly different with Swisher Sweets (0.1% ventilation) Cherry at 1.20 mg nicotine, Cheyenne Menthol (1.5%) at 0.63 mg, and Santa Fe unflavored (49%) at 0.94 mg. The association between nicotine MLI and puff volume was the same between Cheyenne Menthol and Santa Fe unflavored. However, these were different from Swisher Sweets Cherry. At least five main factors�flavor, ventilation, filter design, nicotine delivery related to tar, and user puff volume�may directly or indirectly impact MLI and its association with other measures. We found that users of little filtered cigars that have different filter ventilation and flavor draw dissimilar amounts of nicotine from the product, which may be accompanied by differences in exposure to other harmful smoke constituents.

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The effect of emerging tobacco related products and their toxic constituents on thrombosis

et al. 2022

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Cigar Use Symposium: Epidemiology, Toxicant Exposure, Health and Policy Implications

Cited by 5 publications

References 7 publications

Cigarillo and Little Cigar Mainstream Smoke Constituents from Replicated Human Smoking

Cigarillo and Little Cigar Mainstream Smoke Constituents from Replicated Human Smoking

Mouth Level Intake of Nicotine from Three Brands of Little Filtered Cigars with Widely Differing Product Characteristics Among Adult Consumers

The effect of emerging tobacco related products and their toxic constituents on thrombosis

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