Chryseobacterium indologenes: Case report of an emerging pathogen

Chryseobacteriumspp-associated bacteraemia in a haemodialysis patient: a diagnostic challenge

“…Only <10% reports have come from Australia, Europe and the USA 5. Chryseobacteria are thought to have low pathogenicity with unclear virulence factors but they can produce biofilms on medical implants, and possess protease activity that may help these pathogens in causing invasive infections in hospitalised patients with multiple comorbid illnesses (such as malignancy, chronic kidney disease, hypertension and diabetes) and indwelling vascular catheters 6–8…”

“…In literature, it has been reported that establishment of Chryseobacterium infection in human beings requires the presence of following three factors: (1) the production of a biofilm on foreign materials, (2) a suitable portal of entry and (3) immunodeficiency. Chryseobacterium spp can cause a myriad of infections including bacteremia/sepsis, ventilator-associated pneumonia, indwelling device-associated infection, urinary tract infections, peritonitis, shunt infections, surgical and burn wound infections 7 9. Overall, mortality rate of these infections is high due to delay in pathogen identification, widespread antibiotic resistance and underlying comorbidities of these patients 10.…”

Chryseobacterium indologenes: An Emerging Hospital Infection

“…[12] In the literature, most cases of C. indologenes bacteremia were detected in hospitalized patients with a severe underlying disease, such as malignancies or diabetes mellitus, or indwelling devices. [2][3][4][5][6][7][8] The world literature cites different indwelling devices such as respirators, endotracheal tubes, tracheostomy rubes, and humidifiers responsible for colonization of this pathogen. The organism survives in chlorinated water supplies and can form biofilms, thereby easily colonizing hospital environment or patients through contaminated medical equipment.…”

“…The organism survives in chlorinated water supplies and can form biofilms, thereby easily colonizing hospital environment or patients through contaminated medical equipment. [8] In the hospital environment, these organisms exist in water systems and on wet surfaces of medical tools and equipment. Chryseobacteria are of low pathogenicity.…”

“…[1] It is non-motile, catalase positive, oxidase positive, indole positive, non-glucosefermenting Gram-negative bacilli. C. indologenes has been seen to cause various types of infections such as bacteremia, septicemia, pneumonia, meningitis, artificial shunt infection, and catheter-associated urinary tract infection, [2][3][4][5][6][7][8] especially in those with indwelling devices and those with underlying diseases. Chryseobacterium meningosepticum and C. indologenes are two species most commonly isolated from clinical specimen.…”