Chronic respiratory diseases and lung cancer research: a perspective from the European Union

Navarro-Torné, Adoración; Vidal, María; Trzaska, Dominika; Passante, Lara; Crisafulli, Aldo; Laang, Hannu; Loo, Jan-Willem van de; Berkouk, Karim; Draghia-Akli, Ruxandra

doi:10.1183/13993003.00395-2015

Cited by 22 publications

(12 citation statements)

References 26 publications

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“…In addition, people with lung cancer have an increased risk of developing pneumonia. While, past lung diseases for example recurrent pulmonary infection may be at a greater risk of developing lung cancer 28 . These show the relationship between pneumonia and lung cancer.…”

Section: Discussionmentioning

confidence: 99%

Impact of pneumonia and lung cancer on mortality of women with hypertension

Shen

Tian

Lü

et al. 2016

Sci Rep

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Essential hypertension is one of the most severe women's health problems. Modern life brings more chances of pulmonary diseases to human. The purpose of the study is to investigate weather pneumonia and lung cancer are associated with the mortality of women with hypertension in different age. A crosssectional retrospective study was conducted in women with hypertension, who were admitted into our hospital in 2004-2013. 14219 women were enrolled and 68.8 ± 12.2 year old (y). Isolated hypertension was 14.7%. The age of death was 78.1 ± 9.8 y. The mortality was 4.4% for average and 0.2%, 1.1%, 2.4%, 4.8%, 10.4% and 15.8% in group age ≦49, 50-59, 60-69, 70-79, 80-89 and ≧90 y separately. This mortality increased with age was positively significantly correlated with the increased incidences of pneumonia (P < 0.05, r = 0.77). Pneumonia was a significant risk associated with the mortality in age 55-89 y (OR = 6.4-22.5; 95% CI = 3.06-51.12). While, lung cancer was the significant risk in 70-79 y. These observations indicate that pneumonia and lung cancer are significant risk factors associated with the mortality of certain age women with hypertension, and bring an alert that pneumonia and lung cancer should be prevented and treated intensively in modern life in order to reduce the mortality.Hypertension is one of the most severe health problems for women. The prevalence of it in women is almost the same as man, women vs. men = 26.1-29.5 % vs. 26.6-29.0% 1 . The mortality of it from 2000 through 2013 significantly increased 36.8% for aged 45-64, from 2000 to 2005 increased 23% for those >85 and 10.9% for those 75-84 2 . Women face big challenges to reduce the mortality of hypertension.The most significant distinction between women and men with hypertension is protective effect of estrogen before menopause and reduced protective effect of estrogen after menopause 3 ; therefore, women have unique manifestation of cardiovascular risks and target organ damage with hypertension, they tend to more have relevant age-related risks of mortality. Studying such risks from different age is probably powerful than studying global risks in whole age.Pneumonia is a common disease occurring in all parts of the world 4 . It is among the most common infectious diseases and the most common lower respiratory tract infection 5 . It is a major cause of death among all age groups resulting in 7% of the world's total death yearly 4,6 . Lung cancer is also common worldwide, it is the third highest incidence, and second after breast cancer in mortality among cancer of women 7 . Both pneumonia and lung cancer are diseases of respiratory system, and diseases related to longevity or civilization, that appear to the increase in frequency in modern life as countries become more industrialized and people live longer.Relationship between pneumonia or lung cancer and essential hypertension is not well studied. Pneumonia and lung cancer whether influence the mortality of patients with hypertension lacks of concrete data. So far, only few studies involved i...

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Section: Discussionmentioning

confidence: 99%

Impact of pneumonia and lung cancer on mortality of women with hypertension

Shen

Tian

Lü

et al. 2016

Sci Rep

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“…CRDs include chronic obstructive pulmonary disease (COPD), occupational lung diseases, asthma and respiratory allergies, sleep apnoea syndrome, and pulmonary hypertension. Asthma and COPD account for most of the deaths among CRDs in low and middle-income countries (59)(60)(61). Genetic and environmental factors are the risk factors of CRDs; environmental factors are more dominant.…”

Section: Chronic Respiratory Diseases (Crds)mentioning

confidence: 99%

Management and Prevention Strategies for Non-communicable Diseases (NCDs) and Their Risk Factors

Budrevičiūtė

Damiati

Sabir³

et al. 2020

Front. Public Health

446

247

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Non-communicable diseases (NCDs) are of increasing concern for society and national governments, as well as globally due to their high mortality rate. The main risk factors of NCDs can be classified into the categories of self-management, genetic factors, environmental factors, factors of medical conditions, and socio-demographic factors. The main focus is on the elements of self-management and to reach a consensus about the influence of food on risk management and actions toward the prevention of NCDs at all stages of life. Nutrition interventions are essential in managing the risk of NCDs. As they are of the utmost importance, this review highlights NCDs and their risk factors and outlines several common prevention strategies. We foresee that the best prevention management strategy will include individual (lifestyle management), societal (awareness management), national (health policy decisions), and global (health strategy) elements, with target actions, such as multi-sectoral partnership, knowledge and information management, and innovations. The most effective preventative strategy is the one that leads to changes in lifestyle with respect to diet, physical activities, cessation of smoking, and the control of metabolic disorders.

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“…leading to low immunity and respiratory tract infection. Besides, patients with lung cancer increase chances of developing pneumonia; while, patients with history of lung diseases present increased risk of having lung cancer 33 . All in all, inner-link among hypertension, pneumonia and lung cancer may exist.…”

Section: Discussionmentioning

confidence: 99%

Associations between untraditional risk factors, pneumonia/lung cancer, and hospital fatality among hypertensive men in Guangzhou downtown

Shen

Chen

Huang

et al. 2020

Sci Rep

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Mortality of primary hypertension is high worldwide. Whether untraditional factors exist in modern life and affect the mortality is not well studied. The aim of the study was to evaluate the risk factors for fatality rate of hypertensive men in downtown area. A cross-sectional study was performed on hypertensive men, who were hospitalized into our hospital and lived in eligible urban areas. the characteristics of the patients and factors for the fatality were analyzed and of the risks or the contributors on the status were investigated. 14354 patients were identified. Mean age was 68.9 ± 12.4 year old (y) and dead ones was 75.9 ± 9.5 y. The overall hospitalized fatality was 5.9%, which was increased with age: fatality with 0.7%, 2.2%, 2.9%, 7.1%, 11.1% and 16.6% was for age group ≦ 49 y, 50-59 y, 60-69 y, 70-79 y, 80-89 y and ≧ 90 y respectively. The increased fatality was significantly positively correlated with the incidence of pneumonia, P < 0.05, r = 0.99. Pneumonia was prone to involve in men with older age and severer organ damage by hypertension. Similar to traditional risks such as coronary heart disease and stroke, pneumonia and lung cancer were also significantly associated with the fatality. Odds ratio (95% CI) for pneumonia and lung cancer were 6.18 (4.35-8.78) and 1.55 (1.14-2.11). The study provides evidence that pneumonia and lung cancer are highly associated with fatality of hypertensive men in downtown area, indicating that in order to reduce the fatality of hypertension, these lung diseases should be prevented and treated intensively in modern life. Primary hypertension is one of the most common diseases worldwide; the prevalence reaches 60-80% in elderly 1 and 26% in adult population 2,3. It is also the most important risk for mortality, responsible for globally 13% of deaths 4. Thus the both morbidity and mortality of hypertension are high incredibly in worldwide. Traditional risk factors, such as coronary heart disease (CHD) and stroke, are implicated in the occurrence of death in patients with hypertension. However, the extent to which those risk factors correlated with mortality in such patients remain insufficiently assessed, highlighting a need for efforts toward finding untraditional risks in order to improve outcomes in this population. With the social progress, economic development, population increase and human life spans lengthen ad so on, people's lifestyle changes a lot. Modern life brings people fantastic world. However, the drawbacks exist, such as urban congestion and traffic pollution. One report 5 showed that the proportions of men with hypertension

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Chronic respiratory diseases and lung cancer research: a perspective from the European Union

Cited by 22 publications

References 26 publications

Impact of pneumonia and lung cancer on mortality of women with hypertension

Impact of pneumonia and lung cancer on mortality of women with hypertension

Management and Prevention Strategies for Non-communicable Diseases (NCDs) and Their Risk Factors

Associations between untraditional risk factors, pneumonia/lung cancer, and hospital fatality among hypertensive men in Guangzhou downtown

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