1997
DOI: 10.1590/s0036-46651997000500009
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Chronic pulmonary histoplasmosis in Brazil: report of two cases with cavitation diagnosed by transthoracic needle biopsy

Abstract: Two cases of Chronic Pulmonary Histoplasmosis are reported and other eleven cases, collected from Brazilian literature, are commented. After being clinically cured, one of our patients presented an Aspergillus fungus ball inside a cavitation in the wall of which H. capsulatum was disclosed. Comments are also done on the diagnosis of the mycosis.

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Cited by 11 publications
(11 citation statements)
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“…(12) Only thirteen cases of CPH have been reported in Brazil. (5) Of these, five were CPH with cavitation: three occurring in the state of Rio de Janeiro, (13) and two in the state of Rio Grande do Sul. (5) These two states weight loss Itraconazole -9m ET: empirical treatment (for tuberculosis); M: male; m: months to fibrotic retraction around the emphysematous bulla, which is a pattern characteristic of pulmonary histoplasmosis.…”
Section: Discussionmentioning
confidence: 99%
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“…(12) Only thirteen cases of CPH have been reported in Brazil. (5) Of these, five were CPH with cavitation: three occurring in the state of Rio de Janeiro, (13) and two in the state of Rio Grande do Sul. (5) These two states weight loss Itraconazole -9m ET: empirical treatment (for tuberculosis); M: male; m: months to fibrotic retraction around the emphysematous bulla, which is a pattern characteristic of pulmonary histoplasmosis.…”
Section: Discussionmentioning
confidence: 99%
“…(5) Of these, five were CPH with cavitation: three occurring in the state of Rio de Janeiro, (13) and two in the state of Rio Grande do Sul. (5) These two states weight loss Itraconazole -9m ET: empirical treatment (for tuberculosis); M: male; m: months to fibrotic retraction around the emphysematous bulla, which is a pattern characteristic of pulmonary histoplasmosis. (4) Due to its high sensitivity, the immunodiffusion test is a good trial method for CPH, presenting positive results in virtually 100% of cases in which the diagnosis is later confirmed.…”
Section: Discussionmentioning
confidence: 99%
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“…(10) The radiological aspect of the initial lesion is characterized by foci of interstitial inflammatory infiltrate, adjacent to emphysematous bullae, and the lesion commonly affects the apical and apicoposterior segments of the upper lobes. (2,5,6,10) Thickening of the walls of the bullae is common and is followed by necrosis and increased fibrosis, which leads to lung volume loss. This continuous process culminates with large and persistent cavities that can affect an entire lobe.…”
Section: Acute Symptomatic H Capsulatum Infection Ismentioning
confidence: 99%
“…(3) Chronic pulmonary histoplasmosis is a rare clinical manifestation of the disease that affects the upper lobes of the lungs and can present as cavitation and fibrosis. (4)(5)(6)(7) We report the case of a female patient with chronic cavitary pulmonary histoplasmosis (CCPH). …”
mentioning
confidence: 99%