Chronic periodontitis, a significant relationship with acute myocardial infarction

Abstract

Our findings suggest that patients who at routine dental visits demonstrate evidence of bone loss around several teeth can predictably be identified as being at risk for future AMI. Such subjects should be referred for medical and periodontal examinations and treatments.

Association between Myocardial Infarction and Periodontitis: A Meta-Analysis of Case-Control Studies

“…After their exclusion, 38 articles were selected for further full-text review. Eventually, 17 studies (Emingil et al, 2000; Rutger Persson et al, 2003; Deliargyris et al, 2004; Renvert et al, 2004; Cueto et al, 2005; Andriankaja et al, 2006, 2007; Kaisare et al, 2007; Stein et al, 2009; Willershausen et al, 2009, 2014; Holmlund et al, 2011; Kodovazenitis et al, 2011, 2014; Khosravi Samani et al, 2013; Wożakowska-Kapłon et al, 2013; Rydén et al, 2016) were included in our meta-analysis. A flow diagram of search process and results is shown in Figure 1.…”

“…Thirteen studies were conducted in European countries (Emingil et al, 2000; Rutger Persson et al, 2003; Deliargyris et al, 2004; Renvert et al, 2004; Cueto et al, 2005; Stein et al, 2009; Willershausen et al, 2009, 2014; Holmlund et al, 2011; Kodovazenitis et al, 2011, 2014; Wożakowska-Kapłon et al, 2013; Rydén et al, 2016), 2 studies were conducted in USA (Andriankaja et al, 2006, 2007) and 2 were conducted in Asian countries (Kaisare et al, 2007; Khosravi Samani et al, 2013). Within the included studies, a total of 3456 MI patients and 3875 non-MI control subjects had been evaluated.…”

“…Six studies (Rutger Persson et al, 2003; Deliargyris et al, 2004; Andriankaja et al, 2006, 2007; Stein et al, 2009; Rydén et al, 2016) scored more than 7 points and were considered to be of high quality. Eleven studies (Emingil et al, 2000; Renvert et al, 2004; Cueto et al, 2005; Kaisare et al, 2007; Willershausen et al, 2009, 2014; Holmlund et al, 2011; Kodovazenitis et al, 2011, 2014; Khosravi Samani et al, 2013; Wożakowska-Kapłon et al, 2013) scored less than 6 points but more than 4 points, and these studies were considered to be of moderate quality.…”

“…Moreover, in the MI patients, a significantly higher level of plaque and BOP were identified compared with control subjects, indicating poor oral hygiene in MI patients. However, the reason that MI patients had a higher level of BOP and dental plaque might also be that they had longer stays in the intensive care unit and hospital during which they may not or could not have maintained their daily oral hygiene (Rutger Persson et al, 2003; Renvert et al, 2004). Furthermore, the overall effect revealed that the MI patients had lost more than 4 teeth (difference in means: 4.122, 95% CI: 2.012–6.232, P = 0.000) more than the control subjects.…”

Association between acute myocardial infarction and periodontitis: A case-control study with north Indian population.

“…On the one hand, various studies conducted on different populations have suggested that atherosclerosis and the occurrence of AMI could be linked to periodontal infections (Arbes, Slade & Beck, 1999;Buhlin et al, 2002;Persson, Ohlsson, Pettersson, & Renvert, 2003;Smeets et al, 2001;Stein et al, 2011) However, on the other hand, several recent studies and meta-analyses have failed to identify any association between these two conditions Bokhari, 2006;Bokhari, Khan, Azhar, & Shahbaz, 2009;Humphrey, Fu, Buckley, Freeman & Helfand, 2008;Joshipura et al, 2011;Malthaner et al, 2002;Renvert, Ohlsson, Pettersson & Persson, 2010;Tuominen et al, 2003). After accounting for factors common to both periodontal disease and cardiovascular diseases, these studies found no significant association between periodontal disease and cardiovascular diseases, including AMI.…”