2005
DOI: 10.1007/s00508-005-0464-2
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Chronic pelvic pain treated with gabapentin and amitriptyline: A randomized controlled pilot study

Abstract: Gabapentin alone or in combination with amitriptyline is better than amitriptyline alone in the treatment of female chronic pelvic pain.

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Cited by 132 publications
(100 citation statements)
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“…A recent prospective randomized trial compared the use of gabapentin and amitriptyline or a combination of the two in the treatment of CPP. Pain relief was significantly better in patients receiving gabapentin either alone or in combination with amitriptyline than in those receiving monotherapy with amitriptyline [16].…”
Section: Anticonvulsantsmentioning
confidence: 99%
“…A recent prospective randomized trial compared the use of gabapentin and amitriptyline or a combination of the two in the treatment of CPP. Pain relief was significantly better in patients receiving gabapentin either alone or in combination with amitriptyline than in those receiving monotherapy with amitriptyline [16].…”
Section: Anticonvulsantsmentioning
confidence: 99%
“…Common side effects of tricyclic drugs include constipation, cardiac arrhythmias, urinary retention, and decreased libido. Combination therapies are also useful [19]. Specific medical therapy for associated conditions, such as antispasmodics for irritable bowel syndrome, fiber additives to diet to prevent or treat chronic constipation, hormonal treatment for endometriosis, and pentosan polysulfate and other medications for interstitial cystitis, should be considered in the initial management when the appropriate diagnosis is elicited as the cause for pain.…”
Section: Medical Treatmentmentioning
confidence: 98%
“…De cualquier forma, la respuesta a este tipo de tratamiento conservador es de ligera o moderada mejoría .En una publicació n reciente, encontramos que la gabapentina podría producir una mejoría significativa sola o en asociació n con la amitriptilina para tratar este tipo de dolor 35 .…”
Section: Article In Pressunclassified