CHRONIC OCCLUSIVE DISEASES OF LOWER LIMB ARTERIES IN THE NORTH (Literature Review)

Карпин, Владимир Александрович; Александрович, Карпин Владимир; Мельникова, Екатерина Николаевна; Gudkov, A. B.; Popova, O. N.; Попова, О Н

doi:10.33396/1728-0869-2017-8-37-43

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Простагландины (алпростадил, илопрост) Также необходимо применять лечебную физкультуру -тренировочная дозированная ходьба (45-60 минут в сутки). Она направлена на развитие коллатеральных сосудов, улучшение микроциркуляции и венозного оттока, способствуя улучшению кровоснабжения в ишемизированных тканях НК [14]. Гипербарическая оксигенация оказывает положительное влияние на состояние свертывающей системы крови и микроциркуляцию.…”

Section: Introductionunclassified

Sympathectomy and Neuromodulation in the Treatment of Critical Lower Limb Ischemia

Yarikov

Leonov

Шпагин

et al. 2022

Neotložnaâ med. pomoŝʹ

View full text Add to dashboard Cite

INTRODUCTION Critical lower limb ischemia is a widespread disease that occurs due to atherosclerotic lesions of the arteries with progressive narrowing of their lumen. Clinically critical ischemia is manifested by pain at rest, resistant to narcotic analgesics, and/or ulcerative necrotic process on the legs. In the absence of treatment, patients undergo amputation of the lower limb. Almost all patients die 10 years after amputation of the lower limb at the level of the thigh. Currently, there are following methods of treatment of critical ischemia: conservative therapy, direct revascularization, lumbar sympathectomy and neurostimulation.AIM OF STUDY To present the data of modern scientiﬁ c literature on the use of lumbar sympathectomy and epidural spinal cord stimulation in the treatment of critical lower limb ischemia.MATERIAL AND METHODS This review presents the latest data obtained as a result of studying domestic and foreign literature on the treatment of critical lower limb ischemia with lumbar sympathectomy and epidural spinal cord stimulation. Currently, lumbar sympathectomy is performed by surgical (open, mini-access and endoscopic) and percutaneous (chemical or radiofrequency) methods. Percutaneous access is becoming widespread due to its minimally invasiveness, maximum accessibility, ease of performance and low cost. Epidural spinal cord stimulation is performed for resistant pain syndrome. The mechanism of action of spinal stimulation is to block the transmission of nerve impulses at the level of the gelatinous substance of the posterior horns of the spinal cord during stimulation of afferent ﬁ bers of a larger diameter (type A-alpha and A-beta ﬁ bers).CONCLUSION Spinal neurostimulation and lumbar sympathectomy are promising methods of treatment for critical lower limb ischemia in case of impossibility of direct revascularization. Lumbar sympathectomy can reduce the intensity of pain and improve the quality of life of patients. According to a number of studies, epidural spinal cord stimulation signiﬁ cantly reduces the likelihood of amputation of the lower limb, and also reduces the intensity of pain in patients refractory to conservative therapy, as well as in those who are not indicated for direct revascularization of the arteries of the lower extremities. More large-scale studies are needed to determine the indications for the above methods.

show abstract

Section: Introductionunclassified

Sympathectomy and Neuromodulation in the Treatment of Critical Lower Limb Ischemia

Yarikov

Leonov

Шпагин

et al. 2022

Neotložnaâ med. pomoŝʹ

View full text Add to dashboard Cite

show abstract

A complicated form of spontaneous aortic atherosclerosis in an African green monkeys (Chlorocebus aethiops sabaeus) male. Clinical case

Orlov,

Panchenko,

Shestakov

et al. 2024

RC FCV-LUZ

View full text Add to dashboard Cite

Atherosclerosis is the mechanistic basis of cardiovascular disorders manifested by damage to the walls of the aorta, coronary, cerebral and peripheral arteries, leading to the development of acute or chronic ischemia of internal organs and tissues. This publication describes a case of spontaneous atherosclerotic lesion of the aorta with the formation of a dissecting aneurysm in an African green monkey male. The ancestors were introduced from Ethiopia and Europe. The case monkey was housed as a family group in an outdoor enclosure with attached smaller room equipped with heating system. It lived 16.4 years. Pathological diagnosis was established through complete autopsy and histopathology. Main disease was chronic atrophic gastroenterocolitis in exacerbation complicated with alimentary dystrophy, cachexia (brown atrophy of the myocardium, liver, skeletal muscles). The concomitant diseases: complicated atherosclerosis of the aorta, dissecting abdominal aortic aneurysm with a large cylindrical organized thrombus in the aneurysm area, stenosing atherosclerosis of the renal arteries, vascular wrinkled left kidney; focal atherosclerosis of the coronary arteries and their branches with small foci of atherosclerotic cardiosclerosis and arteriosclerosis of cerebral arteries. The revealed changes indicate a significant similarity in the pathomorphogenesis of atherosclerotic lesions in African green monkey and humans. It allows us to consider this genus of primates as a promising laboratory model for studying the pathogenesis and mechanisms of regression as well as the effectiveness of therapeutic approaches to the treatment of atherosclerosis and its complications.

show abstract

CHRONIC OCCLUSIVE DISEASES OF LOWER LIMB ARTERIES IN THE NORTH (Literature Review)

Cited by 2 publications

References 9 publications

Sympathectomy and Neuromodulation in the Treatment of Critical Lower Limb Ischemia

Sympathectomy and Neuromodulation in the Treatment of Critical Lower Limb Ischemia

A complicated form of spontaneous aortic atherosclerosis in an African green monkeys (Chlorocebus aethiops sabaeus) male. Clinical case

Contact Info

Product

Resources

About