Chronic myeloid leukemia presenting with bilateral central retinal vein occlusion and massive retinal infiltrates

Non‐invasive imaging of retinal blood flow in myeloproliferative neoplasms

“…Visual disturbances may be the presenting symptoms in patients with MPN (Goel et al. ). Cotton‐wool spots and haemorrhages in the retina are common findings (Nobacht et al.…”

Leukostasis in Children and Adolescents with Chronic Myeloid Leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group

“…Hemorrhage may occur at all levels of the retina, usually in the posterior pole, and may extend into the vitreous. The presence of microaneurysms and central retinal vein occlusion are related increased viscosity from elevated leukocyte count in CML . In the present study, retinal abnormalities were determined when the patients were observed in the context of symptoms.…”

“…The presence of microaneurysms and central retinal vein occlusion are related increased viscosity from elevated leukocyte count in CML. [25,26] In the present study, retinal abnormalities were determined when the patients were observed in the context of symptoms. In a prospective ophthalmic evaluation, a higher prevalence of retinal changes (39.5%; 15 out of 38 cases) was observed [24] when compared with the present study (5.9%; 14 out of 237 cases) in newly diagnosed CML.…”

A unique case of chronic myeloid leukemia presenting as monocular vision loss with unilateral retinopathy

“…In patients with CML who present with isolated ocular manifestations, TKI therapy with concomitant ocular surgical intervention has often resulted in improvement in visual acuity and other ocular symptoms 7, 8, 9, 10, 11. Huang et al reported a case of 30 year old male who presented with bilateral multilayer retinal hemorrhage with visual acuities of 20/20 OD and 20/100 OS 7 .…”

“…To date, nine cases have been reported in which the ocular manifestations of CML were the only presenting signs of the disease, however, in all of these cases, ocular involvement was described bilaterally 7, 8, 9, 10, 11. In addition, the disease risk stratification of these patients with CML and symptomatic ocular presentations was not discussed.…”