Chronic liver disease-related mortality in diabetes before and during the COVID-19 in the United States

Kim, Dong‐Hee; Alshuwaykh, Omar; Dennis, Brittany B.; Cholankeril, George; Knowles, Joshua; Ahmed, Aijaz

doi:10.1016/j.dld.2022.09.006

Cited by 6 publications

(5 citation statements)

References 18 publications

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“…In the US, NAFLD‐related mortality increased during the pandemic 8,19 . It should be emphasized that nonalcoholic steatohepatitis and NAFLD are rarely reported in Italian death certificates, making it unfeasible to conduct analyses similar to those undertaken in the US, based on the corresponding ICD‐10 codes K75.8 and K76.0 19,20 .…”

Section: Discussionmentioning

confidence: 99%

“…18 In the US, NAFLD-related mortality increased during the pandemic. 8,19 It should be emphasized that nonalcoholic steatohepatitis and NAFLD are rarely reported in Italian death certificates, making it unfeasible to conduct analyses similar to those undertaken in the US, based on the corresponding ICD-10 codes K75.8 and K76.0. 19,20 The present report relies only on ICD-10 coded conditions mentioned in TA B L E 1 Number of deaths, age-standardized mortality rates, proportional mortality by year of death, and selected nosologic categories analysed as multiple causes of death.…”

Section: Re Sultsmentioning

confidence: 99%

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Mortality related to HCV and other chronic liver diseases in Veneto (Italy), 2008–2021: Changes in trends and age‐period‐cohort effects

Casotto,

Amidei,

Saia

et al. 2023

Liver International

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Background and AimsThe objective of this study was to assess the impact of the COVID‐19 pandemic and direct‐acting antiviral (DAA) agents on mortality related to chronic liver diseases (CLD).MethodsAge‐standardized mortality rates were computed based on CLD as the underlying cause of death (UCOD) and as any mention in death certificates (multiple causes of death‐MCOD). Time trends in age‐standardized mortality rates were investigated using generalized estimation equation models. Additionally, we conducted age, period, and birth cohort (APC) analyses on CLD‐related mortality associated with alcohol and hepatitis C virus (HCV).ResultsBetween 2008 and 2021, among residents in the Veneto region (Northeastern Italy) aged ≥35 years, there were 20 409 deaths based on the UCOD and 30 069 deaths based on MCOD from all CLD. We observed a 4% annual decline in age‐standardized MCOD‐based mortality throughout 2008–2021, with minor peaks corresponding to COVID‐19 epidemic waves. Starting in 2016, the decline in HCV‐related mortality accelerated further (p < .001). A peak in HCV‐related mortality in the 1963–1967 birth cohort was observed, which levelled off by the end of the study period. Mortality related to alcoholic liver disease declined at a slower pace, becoming the most common aetiology mentioned in death certificates.ConclusionsThe study demonstrates a significant decrease in HCV‐related mortality at the population level in Italy with the introduction of DAAs. Continuous monitoring of MCOD data is warranted to determine if this favourable trend will continue. Further studies utilizing additional health records are needed to clarify the role of other CLD etiologies.

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Section: Discussionmentioning

confidence: 99%

Section: Re Sultsmentioning

confidence: 99%

Mortality related to HCV and other chronic liver diseases in Veneto (Italy), 2008–2021: Changes in trends and age‐period‐cohort effects

Casotto,

Amidei,

Saia

et al. 2023

Liver International

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“…Patients with alcoholic liver disease might have disproportionally suffered from a surge in harmful drinking, social isolation, and loss of familial and social support, along with barriers to access to outpatient clinics and rehabilitation services. Another study of US national multiple cause-of-death data reported a marked increase in mortality from CLD and/or cirrhosis among decedents with mention of diabetes, specifically associated with increased mortality from NAFLD and alcohol-related liver diseases[ 38 ].…”

Section: Cld As a Cause Of Death During The Covid-19 Pandemicmentioning

confidence: 99%

Mortality from chronic liver disease: Recent trends and impact of the COVID-19 pandemic

Fedeli¹,

Amidei²,

Casotto³

et al. 2023

World J Gastroenterol

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Coronavirus disease 2019 (COVID-19) has several extrapulmonary symptoms. Gastrointestinal (GI) symptoms are among the most frequent clinical manifestations of COVID-19, with severe consequences reported in elderly patients. Furthermore, the impact of COVID-19 on patients with pre-existing digestive diseases still needs to be fully elucidated, particularly in the older population. This review aimed to investigate the impact of COVID-19 on the GI tract, liver, and pancreas in individuals with and without previous digestive diseases, with a particular focus on the elderly, highlighting the distinctive characteristics observed in this population. Finally, the effectiveness and adverse events of the anti-COVID-19 vaccination in patients with digestive disorders and the peculiarities found in the elderly are discussed.

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“…As a prevalent chronic disease, it has garnered significant attention from researchers [ 3 ]. Additionally, the spread of the coronavirus pandemic has had detrimental effects on individuals with diabetes [ 4 ]. It quickly became evident that people with diabetes were disproportionately affected by the virus, facing an elevated risk of hospitalization and mortality [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

The effect of educational intervention based on social support theory on the perceived stress caused by the covid-19 pandemic in patients with diabetes in hormozgan (2020–2021)

Taheri kondar,

Hassani,

Ghanbarnejad

2024

BMC Public Health

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Background People with diabetes are more at risk of covid-19. Perceived social support plays an important role in maintaining people’s health and reducing the negative effects of stress caused by the environment and society. The present study was designed and implemented with the purpose of determining the effect of educational intervention based on social support theory in reducing stress caused by the covid-19 pandemic in people with diabetes. Methods The current investigation was an interventional and semi-experimental study conducted on 212 patients diagnosed with type 2 diabetes. Eligible participants were diabetic individuals capable of utilizing virtual platforms and not afflicted with COVID-19. Exclusion criteria encompassed unwillingness to continue study participation, absence from multiple training sessions, and development of a specific illness during the study period. Random allocation placed patients into either the control or intervention group. The intervention group received educational materials via WhatsApp, while the control group did not receive any intervention. The researcher administered a questionnaire to collect demographic information and assess perceived social support among the patients. Data analysis involved the use of chi-square tests, independent and paired t-tests, as well as ANCOVA. Results This study revealed that the mean age of patients in the control and intervention groups was 46.35 ± 14.15 and 51.72 ± 11.57, respectively. Most of the diabetic patients in both groups were female, married, had a diploma, were housekeepers, and had an income between 2 and 5 million Tomans. According to the results obtained in all subscales of social support theory as well as the perceived stress score due to the corona pandemic after the educational intervention, a statistically significant difference was observed between the two groups (P < 0.05), so that the score of all subscales of social support theory in the intervention group was higher than the control group. But the perceived stress score caused by Corona in the intervention group was significantly lower than the control group. Conclusion The results of this study illustrate the noteworthy influence of social support training in lessening perceived stress among patients with diabetes during the COVID-19 pandemic. Consequently, healthcare providers are encouraged to integrate social support education programs into comprehensive care initiatives for diabetic patients, particularly during periods of heightened stress like the current coronavirus pandemic.

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Chronic liver disease-related mortality in diabetes before and during the COVID-19 in the United States

Cited by 6 publications

References 18 publications

Mortality related to HCV and other chronic liver diseases in Veneto (Italy), 2008–2021: Changes in trends and age‐period‐cohort effects

Mortality related to HCV and other chronic liver diseases in Veneto (Italy), 2008–2021: Changes in trends and age‐period‐cohort effects

Mortality from chronic liver disease: Recent trends and impact of the COVID-19 pandemic

The effect of educational intervention based on social support theory on the perceived stress caused by the covid-19 pandemic in patients with diabetes in hormozgan (2020–2021)

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