Chronic kidney disease and the aging population

Riella, Miguel C.

doi:10.1007/s40620-014-0038-3

Cited by 17 publications

(15 citation statements)

References 26 publications

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“…Chronic Kidney Disease (CKD) is a general health risk factor worldwide with a higher prevalence in individuals older than 60 years old [ 1 , 2 ]. The CKD refers to a type of kidney disease in which the kidneys lose more than 50% of normal function [ 3 ] and is defined as the presence of kidney damage or an estimated Glomerular Filtration Rate (eGFR) below 60 ml/min/1.73 m 2 persisting at least for 3 months [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial

et al. 2021

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Background End-Stage Renal Disease (ESRD) is the final and permanent stage of Chronic Kidney Disease (CKD). Hemodialysis (HD) is the most common treatment for CKD. To have desirable therapeutic outcomes, patients have to adhere to a specific therapeutic regimen that reduces the hospitalization rate and side-effects of HD. The present study aimed to determine the effects of the patient education program and nurse-led telephone follow-up on adherence to the treatment in hemodialysis patients. Methods This is a randomized controlled trial in which a total of 66 patients were recruited using convenience sampling and then randomly assigned to two groups of control (n = 33) and intervention (n = 33). Data were collected using a demographic questionnaire, the laboratory results record sheet, and the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ), which included four dimensions of HD attendance, medication use, fluid restrictions, and diet recommendations. The intervention group received a patient education program and nurse-led follow-up services through telephone communication and the Short Message Service (SMS) for 3 months. All participants filled in the questionnaire before and after the intervention. Data were analyzed using IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, N.Y., USA). Results The results showed a significant difference in the mean scores of HD attendance, medication use, fluid restrictions, and diet recommendations between the two groups immediately, 1 month, and 3 months after the intervention (p < .001). The results also indicated a significant difference in the mean scores of four dimensions during the four-time points of measurement in the intervention group (P < 0.0005). Therefore, the level of treatment adherence in the intervention group was higher than in the control group. Moreover, there was a significant difference in the mean score of laboratory values between the two groups after the intervention, except for the level of serum sodium (P = 0.130). Conclusion Implementation of the patient education program and nurse-led follow-up can lead to better adherence to hemodialysis in four dimensions of HD attendance, medication use, fluid restrictions, and dietary recommendations in HD patients. Trial registration IRCT registration number: IRCT20190127042512N1; Registration date: 2020-09-12; Registration timing: retrospectively registered: Last update: 2020-09-12.

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Section: Introductionmentioning

confidence: 99%

Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial

et al. 2021

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“…Providing individual patients with specific prognostic data and evaluating their suitability for surgery is often a challenge. Patients with advanced kidney disease often request information on whether the surgery will precipitate a requirement for permanent dialysis [8].…”

Section: Discussionmentioning

confidence: 99%

Outcome stratification of patients with impaired renal functions after isolated prosthetic mitral valve replacement

Hassan¹,

Elbadawi²,

Elsayed³

et al. 2021

GSC Adv. Res. Rev.

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Objectives: Patients with impaired renal functions have a variable risk of morbidity and mortality in cardiovascular surgery. Poor outcome was reported among patients who underwent valve surgery. Current study is presumed to compare the early outcomes of patients having different degrees of impaired renal functions and undergoing mitral valve replacement surgery. Methods: 135 patients were admitted into the three highly specialized centers in Cairo and Ismailia–Egypt between Dec.2018 and Jan.2020 Preoperative, intraoperative and early post-operative data were recorded. Impairment may present as one of these strata: early reversible (G1-2 included strata 1 & 2 kidney disease patients), moderate G3-4 included strata 3 & 4 kidney disease patients) or advanced irreversible renal damage. (The 5th stratum or G5-KD included end stage renal disease patients undergoing 4-hour hemodialysis sessions, three times a week, with bicarbonate dialysate). We correlated outcome among each stratum with cardiac and renal functions in that stratum. Results: The more is the impairment of renal functions at any peri- operative stage, the longer is the need for prolonged mechanical ventilation and the longer is the hospital stay. We found that levels of serum creatinine were significantly increased postoperatively Also, the more is the reversibility of the renal impairment, even by renal dialysis, the much better is the outcome (P=.0019). We also found insignificant difference between different strata of irreversible renal impairment in the early outcome of the prosthetic mitral valve replacement surgery. The early reversible damage can be repaired peri-operatively. Conclusions: Prosthetic mitral valve replacement among patients with different degrees of impaired renal functions is not only feasible but also it does not seem to add any more deterioration into renal function. Prolonged mechanical ventilation and hospital stay are the only drawbacks of irreversibly impaired renal damage by dialysis or renal transplant.

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“…The prevalence of elderly CKD is expected to increase further if the current preventive measures against CKD remains unchanged. It has been suggested that age-specific care considerations should be incorporated into the scope of management for elderly patients with CKD [92,93]. To name just a few, GFR thresholds for diagnosing CKD may be adjusted downward to 45-50 mL/min/1.73 m 2 , based on mortality outcomes stratified by levels of GFR in the general population [9,94].…”

Section: Treatment and Care Management For The Elderlymentioning

confidence: 99%

Aging and Renal Disease: Old Questions for New Challenges

Chou¹,

Chen²

2021

Aging and disease

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Chronic kidney disease (CKD) is a growing problem among aging population, and the number of individuals at risk of end stage renal disease is rising. Part of the reason lies in incomplete understanding of the pathways underlying renal aging and kidney disease, as well as insufficient delivery of evidence-based treatment to elderly patients with CKD. This review aims to address these unsolved issues by delineating updated mechanisms of renal senescence and summarizing recent findings on key clinical aspects of CKD in the elderly. Challenges and obstacles in caring for older people with CKD are discussed, with an emphasis on modification of risk factors, prevention of acute kidney injury, stabilization of progression and decision on dialysis initiation.

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Chronic kidney disease and the aging population

Cited by 17 publications

References 26 publications

Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial

Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial

Outcome stratification of patients with impaired renal functions after isolated prosthetic mitral valve replacement

Aging and Renal Disease: Old Questions for New Challenges

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