Chronic granulomatous mastitis: A therapeutic dilemma revisited

Kshirsagar, Vinayak; Male, Prashant; Bendre, Mahendra; Chavan, Shahaji; Rathod, Sarang

doi:10.4103/2278-9596.194983

Cited by 3 publications

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“…Surgical treatment is a complete and effective treatment; frozen section during surgery and postoperative pathological examination should be performed to confirm the diagnosis. If there are no postoperative complications and recurrence, relapsing the patients do not need for other medicines [5][6][7][8]50]. Due to the fact that surgery alters the appearance of the breast, physicians might recommend oral steroids as effective treatment for patients who require maintenance of the appearance of the breast.…”

Section: Discussionmentioning

confidence: 99%

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The Effect of Western Medicine Therapies on Granulomatous Mastitis: a Meta-analysis

et al. 2019

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Section: Discussionmentioning

confidence: 99%

“…A total of 87 articles were eliminated because they did meet the inclusion criteria after reading the full article. Thirty articles were involved in the final analysis [4,[6][7][8]. Twenty-three articles were in English and seven were in Chinese.…”

Section: Literature Searchmentioning

confidence: 99%

The Effect of Western Medicine Therapies on Granulomatous Mastitis: a Meta-analysis

et al. 2019

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Outcomes from treatment of Granulomatous lobular mastitis

Olimpiadi

Brownson

Ding

et al. 2021

Surgery in Practice and Science

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Role of empirical antitubercular therapy for chronic mastitis—A prospective study

Baby,

Hari,

Paul

et al. 2024

Indian J Breast Imaging

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Objectives Chronic mastitis (CM) is an uncommon inflammatory condition of the breast, clinically mimicking malignancy with variable etiological factors. It often recurs, causing cosmetic disfigurement and hampering the quality of life of affected females. Limited literature reveals underlying bacterial infection as causative agents in a few cases, while the majority belong to idiopathic entities. CM can be seen as two histological types—chronic granulomatous mastitis (CGM) and chronic nonspecific inflammatory infiltrates (NGM). Etiological and ethnic variations exist globally, and there is lack of information from India. Understanding this entity is important for undertaking etiology-based therapy and preventing unnecessary mismanagement. Materials and Methods We evaluated the demographic, imaging profile and management protocol of CM patients presenting to a tertiary care center in India. Clinically suspected CM patients were prospectively evaluated by mammography and ultrasound (USG). USG-guided biopsy was performed for histopathological and microbiological analysis and treatment was administered accordingly. Response assessment was conducted at six months through USG and clinical evaluation. Results Out of the 53 clinically suspected CM patients, 48 biopsy-proven CM patients were enrolled (five breast carcinoma cases were excluded). All 48 patients were females, with a mean age of 36 ± 9 years. The most common symptom was a unilateral painful lump with skin discoloration. The etiology was idiopathic in 58.3% of cases, tuberculosis in 29%, and bacterial in 4%. Mammography revealed focal asymmetry, architectural distortion, and trabecular thickening. USG showed tracking fluid collections, microlobulated hypoechoic masses, and skin thickening. Etiology-based treatment was administered, and all patients showed 90–100% resolution between four and six months. Conclusion Mammography and USG are important for raising the suspicion while histopathology and microbiological analysis are mandatory for accurate treatment of CM. In India, idiopathic and tubercular etiology of CM is encountered and patients respond well to therapy.

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Chronic granulomatous mastitis: A therapeutic dilemma revisited

Cited by 3 publications

References 0 publications

The Effect of Western Medicine Therapies on Granulomatous Mastitis: a Meta-analysis

The Effect of Western Medicine Therapies on Granulomatous Mastitis: a Meta-analysis

Outcomes from treatment of Granulomatous lobular mastitis

Role of empirical antitubercular therapy for chronic mastitis—A prospective study

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