Chronic fatigue syndrome and myalgic encephalomyelitis: towards an empirical case definition

Jason, Leonard A.; Kot, Bobby; Sunnquist, Madison; Brown, Abigail; Evans, Meredyth; Jantke, Rachel; Williams, Yolonda; Furst, Jacob; Vernon, Suzanne D.

doi:10.1080/21642850.2015.1014489

Cited by 42 publications

(65 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The SEID case definition captures 88% of participants in the samples analyzed, which is comparable to the 92% that met the Fukuda criteria [2]. Fewer individuals met the ME/CFS [7] criteria, and still fewer met the ME-ICC [9], and four item empiric criteria [11]. Of those who met the SEID criteria [12], 98% met the CFS Fukuda criteria [2], 85% met the ME/CFS criteria [7], 66% met the ME-ICC criteria [9], and 66% met the a four item empiric criteria [11].…”

Section: Resultsmentioning

confidence: 99%

“…Data mining analyses indicated the selection of four symptoms: fatigue or extreme tiredness, difficulty finding the right word to say or expressing thoughts, physically drained/sick after mild activity, and unrefreshing sleep [11]. In particular, these were all symptoms that appeared in a majority of the 100 classification trees.…”

Section: Methodsmentioning

confidence: 99%

“…Using a more empirical approach, Jason et al [11] used several methods (i.e., continuous scores of symptoms, theoretically and empirically derived cut off scores of symptoms) to identify core symptoms best differentiating patients from controls. Data mining with decision trees was used to identify core that were most effective at accurately classifying participants as patient or control.…”

mentioning

confidence: 99%

“…For most analyses, only 3–5 variables were needed to classify participants. [11] Outcomes from these analyses suggest that individuals with CFS could be accurately identified using only 4 empirically selected symptoms: fatigue or extreme tiredness, physically drained/sick after mild activity, difficulty finding the right word to say or expressing thoughts, and unrefreshing sleep.…”

mentioning

confidence: 99%

“…As with the Jason et al [8,11] studies, the IOM authors recommended using frequency and severity ratings with clear cut off points. [12] This new case definition, newly named Systemic Exertion Intolerance Disease (SEID), has never been compared to other consensus based criteria, nor to the four item empiric criteria [11]. The current study is one of the first to compare this SEID criteria [12] to other diagnostic criteria.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Chronic fatigue syndrome versus systemic exertion intolerance disease

Jason

Sunnquist

Brown

et al. 2015

Fatigue: Biomedicine, Health & Behavior

Self Cite

View full text Add to dashboard Cite

Background The Institute of Medicine has recommended a change in the name and criteria for Chronic Fatigue Syndrome (CFS), renaming the illness Systemic Exertion Intolerance Disease (SEID). The new SEID case definition requires substantial reductions or impairments in the ability to engage in pre-illness activities, unrefreshing sleep, post-exertional malaise, and either cognitive impairment or orthostatic intolerance. Purpose In the current study, samples were generated through several different methods and were used to compare this new case definition to previous case definitions for CFS, Myalgic Encephalomyelitis (ME-ICC), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), as well as a case definition developed through empirical methods. Methods We used a cross-sectional design with samples from tertiary care settings, a biobank sample, and other forums. 796 patients from the US, Great Britain, and Norway completed the DePaul Symptom Questionnaire. Results Findings indicated that the SEID criteria identified 88% of participants in the samples analyzed, which is comparable to the 92% that met the Fukuda criteria. The SEID case definition was compared to a four item empiric criteria, and findings indicated that the four item empiric criteria identified a smaller, more functionally limited and symptomatic group of patients. Conclusion The recently developed SEID criteria appears to identify a group comparable in size to the Fukuda et al. criteria, but a larger group of patients than the Canadian ME/CFS and ME criteria, and selects more patients who have less impairment and fewer symptoms than a four item empiric criteria.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Chronic fatigue syndrome versus systemic exertion intolerance disease

Jason

Sunnquist

Brown

et al. 2015

Fatigue: Biomedicine, Health & Behavior

Self Cite

View full text Add to dashboard Cite

show abstract

Effects of unsupportive social interactions, stigma, and symptoms on patients with myalgic encephalomyelitis and chronic fatigue syndrome

McManimen

McClellan

Stoothoff

et al. 2018

Journal Community Psychology

Self Cite

View full text Add to dashboard Cite

Prior research has found a heightened risk of suicide in patients with myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS). It is possible that a number of factors including stigma, unsupportive social interactions, and severe symptoms could lead to the development of depression, suicidal ideation, and heightened risk of suicide in this patient population. Prior studies have indicated that patients often report the legitimacy of their illness being questioned by family, friends, and even their physicians. This study aimed to determine whether stigma experienced, social support, symptomology, and functioning may be associated with depression and endorsement of suicidal ideation (SI) in patients with a self‐reported diagnosis of ME or CFS. Findings indicated that participants that endorsed both SI and depression, in contrast to those that did not, experienced more frequent unsupportive social interactions in the form of blame for their illness, minimization of its severity, and social distancing from others. In addition, 7.1% of patients with ME and CFS endorsed SI but do not meet the criteria for clinical depression These findings highlight the importance of stigma and unsupportive social interactions as risk factors for suicidal thoughts or actions among patients with ME and CFS. Community psychologists have an important role to play in helping educate health care professionals and the public to these types of risk factors for patients marginalized by ME and CFS.

show abstract

Post-Corona-Fatigue – das bekannte Bild in neuem Gewand?

2022

View full text Add to dashboard Cite

QR-Code scannen & Beitrag online lesen Zusammenfassung Hintergrund: Die myalgische Enzephalitis oder das "chronic fatigue syndrome" (ME/CFS) ist als Folge von COVID(Corona Virus Disease)-19 erneut in den Fokus gerückt. Grundsätzlich problematisch ist die Tatsache, dass ME/CFS als eigenständige Entität gilt, aber extreme Fatigue auch ein häufiges Symptom einer zugrunde liegenden Erkrankung ist. Ziel des Beitrags ist es, die Akzeptanz für ME/CFS und extreme Fatigue bei nicht vollumfänglich verstandener Symptomatologie zu erhöhen und den Bedarf an Forschung, Orientierung für niedergelassene Ärzte sowie an Beratungsangeboten für Patienten hervorzuheben Material und Methoden: Orientierende Recherchen in Form einer fokussierten Informationsbeschaffung. Ergebnisse: In verschiedenen Forschungsprojekten konnte die Hypothese von postinfektiöser ME/CFS als Autoimmunerkrankung bestätigt werden. Generell erschweren sowohl die Heterogenität der diagnostischen Kriterien als auch die Vielfalt von Formulierungen zur Beschreibung der Symptomatik sowie verschiedene Codierungsmöglichkeiten eine klare Zuordnung der Symptome zu einem Krankheitsbild. Belastungsintoleranz wurde als schwerwiegendes Symptom einer Post-COVID-19-Erkrankung identifiziert. Aus diesem Grund werden aktuell die Empfehlungen in internationalen Leitlinien insbesondere hinsichtlich von Pacing überarbeitet. Die Auswirkungen auf Empfehlungen bei tumorbedingter Fatigue oder bei MS sind unklar. Schlussfolgerung: Vor dem Hintergrund eines abnehmenden "burden of disease" durch steigende Impfraten sollte die Forschung zu Fatigue nicht nur viral bedingte Erkrankungen umfassen. Schlüsselwörter Myalgische Enzephalitis • "Chronic fatigue syndrome" • ME/CFS • "Post-exertional malaise" • PEM • Belastungsintoleranz • Pacing

show abstract

Chronic fatigue syndrome and myalgic encephalomyelitis: towards an empirical case definition

Cited by 42 publications

References 36 publications

Chronic fatigue syndrome versus systemic exertion intolerance disease

Chronic fatigue syndrome versus systemic exertion intolerance disease

Effects of unsupportive social interactions, stigma, and symptoms on patients with myalgic encephalomyelitis and chronic fatigue syndrome

Post-Corona-Fatigue – das bekannte Bild in neuem Gewand?

Contact Info

Product

Resources

About