Chronic Exposure to Pesticides- Neurological, Neurobehavioral and Molecular Targets of Neurotoxicity

B.K, Binukumar; Gill, Kiran Dip

doi:10.5772/17276

Cited by 5 publications

(1 citation statement)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5,7 The disorder of neurobehavioral performance due to pesticide exposure includes adverse changes in both the central and peripheral nervous system, resulting in changes in memory, mood, attention, thinking irregularities, and disorientation. 8 The other symptoms are difficulty concentrating, dizziness, persistent headaches, excessive fatigue, and insomnia. 9 Disorders of the nervous system depend on the dose, frequency of exposure, type of pesticides, toxicity, and pesticide exposure duration.…”

Section: Introductionmentioning

confidence: 99%

Neurobehavioral performance of Indonesian farmers and its association with pesticide exposure: A cross-sectional study

Pawestri

Sulistyaningsih

2021

Clinical Epidemiology and Global Health

View full text Add to dashboard Cite

Background: Acute and chronic pesticide exposure affect human health. The study aimed to assess the neurobehavioral performance and its association with pesticide exposure factors among Indonesian farmers. Methods: A cross-sectional study was conducted among farmers living in Jember, Indonesia. Basic individual characteristics and pesticide exposure factors were documented using questionnaire-based interviews. The neurobehavioral performance was assessed by the German Q18 questionnaire and the WHO Neurobehavioral Core Test Battery (NCTB) consists of the Digit Span, Digit Symbol, Pursuit Aiming, and Trail making instruments. Data were presented descriptively and analyzed statistically using the chi-square test. Results: As many as 90 farmers were recruited. Most farmers were 45-55 years old and had a normal nutritional status and moderate smokers. The neurobehavioral performance of the farmers was 62.22% normal and 37.78% abnormal. The most common neurobehavioral deficits were short memory, concentration difficulties, excessive fatigue, frequent headache, and tremor. The chi-square test showed that the spraying frequency (p = 0.006), the spraying duration (p = 0.002), the working years (p = 0.013), and the PPE usage (p = 0.022) associated with neurobehavioral performance, but the pesticide types (p = 0.289) and spraying time (p = 0.627) did not associated with neurobehavioral performance. Conclusion: Although most farmers showed a normal neurobehavioral performance, some pesticide exposure factors demonstrated an association with neurobehavioral performance among Indonesian farmers. Multiple approaches including implementation of the regulation, choosing alternative biopesticides, and regular counseling on all aspects of pesticides, their impact on health are recommended to minimize pesticides' negative effects.

show abstract