Chronic Eosinophilic Pneumonia Presenting With Recurrent Massive Bilateral Pleural Effusion

Samman, Yaseen S.; Wali, Siraj; Abdelaal, M.; Gangi, Mohsin T.; Krayem, Ayman

doi:10.1378/chest.119.3.968

Cited by 30 publications

(18 citation statements)

References 9 publications

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“…2. Pleural effusions have been reported as a rare manifestation of CEP, as has radiographic cavitation (93,161). Pulmonary function testing is often impaired on disease onset, but the pattern of impairment may be either obstructive or restrictive (105).…”

Section: T Cells Also Have a Likely Role In Cep With Increases In mentioning

confidence: 99%

Eosinophilic Pneumonias

Akuthota

Weller

2012

Clin Microbiol Rev

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SUMMARY This review starts with discussions of several infectious causes of eosinophilic pneumonia, which are almost exclusively parasitic in nature. Pulmonary infections due specifically to Ascaris , hookworms, Strongyloides , Paragonimus , filariasis, and Toxocara are considered in detail. The discussion then moves to noninfectious causes of eosinophilic pulmonary infiltration, including allergic sensitization to Aspergillus , acute and chronic eosinophilic pneumonias, Churg-Strauss syndrome, hypereosinophilic syndromes, and pulmonary eosinophilia due to exposure to specific medications or toxins.

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Section: T Cells Also Have a Likely Role In Cep With Increases In mentioning

confidence: 99%

Eosinophilic Pneumonias

Akuthota

Weller

2012

Clin Microbiol Rev

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“…Nonperipheral distribution of consolidations is seen in one third of cases. Rarely does CEP lead to cavitation, atelectasis, pleural effusion (24) or nodular infiltrate. In virtually all cases, CT scans reveal bilateral peripheral foci of airspace need long-term treatment due to asthma severity or recurrence.…”

Section: Forms Of Pulmonary Eosinophilia Simple Pulmonary Eosinophiliamentioning

confidence: 99%

Eosinofilia pulmonar

Campos

Pereira

2009

J. bras. pneumol.

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Pulmonary eosinophilia comprises a heterogeneous group of diseases defined by eosinophilia in pulmonary infiltrates (bronchoalveolar lavage fluid) or in tissue (lung biopsy specimens). Although the inflammatory infiltrate is composed of macrophages, lymphocytes, neutrophils and eosinophils, eosinophilia is an important marker for the diagnosis and treatment. Clinical and radiological presentations can include simple pulmonary eosinophilia, chronic eosinophilic pneumonia, acute eosinophilic pneumonia, allergic bronchopulmonary aspergillosis and pulmonary eosinophilia associated with a systemic disease, such as in Churg-Strauss syndrome and hypereosinophilic syndrome. Asthma is frequently concomitant and can be a prerequisite, as in allergic bronchopulmonary aspergillosis and Churg-Strauss syndrome. In diseases with systemic involvement, the skin, the heart and the nervous system are the most affected organs. The radiological presentation can be typical, or at least suggestive, of one of three types of pulmonary eosinophilia: chronic eosinophilic pneumonia, acute eosinophilic pneumonia and allergic bronchopulmonary aspergillosis. The etiology of pulmonary eosinophilia can be either primary (idiopathic) or secondary, due to known causes, such as drugs, parasites, fungal infection, mycobacterial infection, irradiation and toxins. Pulmonary eosinophilia can be also associated with diffuse lung diseases, connective tissue diseases and neoplasia.Keywords: Pulmonary eosinophilia; Hypereosinophilic syndrome; Aspergillosis, allergic bronchopulmonary; Churg-Strauss syndrome. ResumoAs formas de eosinofilia pulmonar constituem um grupo heterogêneo definido pela presença de um ou dois critérios: infiltrado pulmonar com eosinofilia sanguínea e/ou eosinofilia tissular caracterizada por eosinófilos demonstrados na biópsia pulmonar ou no lavado broncoalveolar. Embora o infiltrado inflamatório seja composto de macrófagos, linfócitos, neutrófilos e eosinófilos, a presença de eosinofilia é um marcador importante para o diagnóstico e tratamento. A apresentação clínica e radiológica pode revelar eosinofilia pulmonar simples, pneumonia eosinofílica crônica, pneumonia eosinofílica aguda, aspergilose broncopulmonar alérgica e eosinofilia pulmonar associada à doença sistêmica, como na síndrome de Churg-Strauss e na síndrome hipereosinofílica. A asma está frequentemente associada, podendo ser um pré-requisito, como na aspergilose broncopulmonar alérgica e na síndrome de Churg-Strauss. Nas doenças com acometimento sistêmico, a pele, o coração e o sistema nervoso são os órgãos mais comprometidos. A apresentação radiológica pode ser considerada como típica, ou pelo menos sugestiva, para três formas de eosinofilia pulmonar: pneumonia eosinofílica crônica, aspergilose broncopulmonar alérgica e pneumonia eosinofílica aguda. A etiologia da eosinofilia pulmonar pode ser de causa primária (idiopática) ou secundária, compreendendo causas conhecidas, como drogas, parasitas, infecções por fungos e micobactérias, irradiação e toxinas. A eosinof...

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“…La presencia de fibrosis en la biopsia apoya el diagnóstico de NEC, hallazgo presente en nuestro caso. La eosinofilia en el LBA es un hallazgo presente en todos los casos, con un recuento promedio de 58% 13 .…”

Section: Discussionunclassified