Eosinophilic Pneumonias

Akuthota, Praveen; Weller, Peter F.

doi:10.1128/cmr.00025-12

Cited by 101 publications

(100 citation statements)

References 219 publications

(257 reference statements)

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“…Eosinophilia can be seen in both the BAL and serum in coccidioidomycosis although the percentage in our patient is higher than usually seen in coccidioidomycosis which averages about 8% (4). BAL eosinophilia is seen, often over 50%, in acute eosinophilic pneumonia (5). In contrast to chronic eosinophilic pneumonia, the peripheral eosinophil count is usually no elevated in acute eosinophilic pneumonia.…”

Section: Correct! 2 the High Percentage Of Eosinophils Is Consistentmentioning

confidence: 99%

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June 2107 pulmonary case of the month

Horsley¹,

Wesselius²

2017

Southwest J Pulm Crit Care

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Section: Correct! 2 the High Percentage Of Eosinophils Is Consistentmentioning

confidence: 99%

“…A number of infectious and noninfectious causes can result in eosinophilic pneumonia (5). Most of the infectious causes are parasites and include ascaris, hookworm, schistosomiasis, and strongyloidiasis.…”

Section: Correct! 5 All Of the Abovementioning

confidence: 99%

June 2107 pulmonary case of the month

Horsley¹,

Wesselius²

2017

Southwest J Pulm Crit Care

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“…Chronic eosinophilic pneumonia (CEP) is defined as eosinophilic pneumonia for more than 2 wk and is the most common subtype in eosinophilic lung diseases [51,52] . It is clinically characterized by eosinophilia, and coexistence…”

Section: Chronic Eosinophilic Pneumoniamentioning

confidence: 99%

“…Imaging of community-acquired pneumonia of atopic medial otitis and asthma [51,52] . Chest radiograph typically shows bilateral nonsegmental consolidations with peripheral predominance [51,52] .…”

mentioning

confidence: 99%

Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases

Nambu

Ozawa

Kobayashi

et al. 2014

WJR

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This article reviews roles of imaging examinations in the management of community-acquired pneumonia (CAP), imaging diagnosis of specific CAP and discrimination between CAP and noninfectious diseases. Chest radiography is usually enough to confirm the diagnosis of CAP, whereas computed tomography is required to suggest specific pathogens and to discriminate from noninfectious diseases. Mycoplasma pneumoniae pneumonia, tuberculosis, Pneumocystis jirovecii pneumonia and some cases of viral pneumonia sometimes show specific imaging findings. Peribronchial nodules, especially tree-in-bud appearance, are fairly specific for infection. Evidences of organization, such as concavity of the opacities, traction bronchiectasis, visualization of air bronchograms over the entire length of the bronchi, or mild parenchymal distortion are suggestive of organizing pneumonia. We will introduce tips to effectively make use of imaging examinations in the management of CAP. Key words: Community-acquired pneumonia; Computed tomography; Infection; Pneumonia; Lung disease Core tip: This review article discusses imaging diagnosis of community-acquired pneumonia (CAP). As imaging findings of CAP are considered nonspecific, this topic is rarely focused on in radiology journals. However, we believe that imaging examinations contribute much more than generally considered if detailed evaluation of the imaging findings is made. In this article, we will introduce tips to effectively make use of imaging examinations in the management of CAP. Nambu A, Ozawa K, Kobayashi N, Tago M. Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases. World J Radiol 2014; 6(10): 779-793 Available from:

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“…Although our understanding of the pathophysiology of CEP is incomplete, studies of BAL fluid from patients with CEP show elevations of several cytokine, chemokine, and immunomodulatory products (17)(18)(19), which suggests that a multifactorial process is involved in the recruitment of eosinophils into the lung (20). Although no reports have suggested an association between smoking and CEP, there is significant overlap between CEP and acute EP, for which a strong association exists with cigarette smoking (20), in the presence of specific common inflammatory mediators in the BALF (20). Smoking causes cellular and molecular changes that can lead to inflammation.…”

Section: Discussionmentioning

confidence: 99%

The Long-term Clinical Course of Chronic Eosinophilic Pneumonia

Ishiguro¹,

Takayanagi²,

Uozumi

et al. 2016

Intern. Med.

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Objective The long-term clinical course and prognosis of patients with chronic eosinophilic pneumonia (CEP) including factors predictive of the relapse of CEP have not been fully investigated. The aim of the present study was to investigate these issues. Methods We retrospectively investigated the rate of relapse and prognosis in 73 patients diagnosed as having CEP. Results Systemic corticosteroid therapy was administered at a prednisolone dose of 29.4±7.6 mg/day. During a median follow-up period of 1,939 days, 27 patients suffered from relapse of CEP. Two patients developed steroid-induced diabetes mellitus, and 1 patient developed pulmonary nontuberculous mycobacteriosis. Five patients died; however, none died of CEP. A history of smoking was the only independent negative risk factor for relapse of CEP [hazard ratio, 0.37 (0.14-0.98)]. Conclusion Patients with CEP frequently relapse. During the follow-up, metabolic and infectious complications under prolonged corticosteroid therapy are problematic. A history of smoking was a negative factor for predicting the risk of CEP relapse.

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Eosinophilic Pneumonias

Cited by 101 publications

References 219 publications

June 2107 pulmonary case of the month

June 2107 pulmonary case of the month

Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases

The Long-term Clinical Course of Chronic Eosinophilic Pneumonia

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