Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level

Kearns, Karen; Dee, Anne; Fitzgerald, Anthony P.; Doherty, Edel; Perry, Ivan J.

doi:10.1186/1471-2458-14-143

Cited by 182 publications

(142 citation statements)

References 27 publications

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“…1,6,3,17 The high prevalence of schools which had unsatisfactory rating or explicit criticizing that the managers, the school community and the health sector have been facing barriers in the articulation and execution of these initiatives in the school environment. The participation of the community is one of the requisites for classifying a school as a health promoter.…”

Section: Discussionmentioning

confidence: 99%

“…9,14,30 as well as the current epidemiological framework regarding the overweight in this group, 3,4,6 demand measures of prevention to the aggravations associated to obesity and more integrated initiatives promoting health.…”

Section: Discussionmentioning

confidence: 99%

“…1 In Brazil, CNCD are responsible for 72.7% of the deaths, 2 emphasizing that overweight and obesity are the main contributors for the charge of chronic diseases in the population. 3 Researches show that part of these health problems has its origins in the childhood or adolescence. 4,5 In the perspective defined by life course epidemiology, early preventive strategies are emphasized so that they guarantee, for example, appropriated nutrition during the phases and actions which build favorable environments to health and also support healthy choices.…”

Section: Introductionmentioning

confidence: 99%

“…[13][14] In Brazil, such objectives are endorsed in the National Policy of Health Promotion and the Health Program at School (PSE -Programa de Saúde da Escola), which has intersecto-riality as one of its main guidelines. 15 These initiatives can be evaluated based on three interrelated components:1) integral health education, 2) creation and maintenance of physical and psychosocial healthy environments, 3) and the offer of health services, healthy eating and active life. 14 The presence of these components in schools may promote healthy eating behaviors and the practice of physical activity, which are fundamental measures for a healthy life and for the prevention of chronic non-communicable diseases in adult life.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Health and nutrition in public and private schools in the city of Recife

Bezerra

Carvalho

Oliveira

et al. 2017

Rev. Bras. Saude Mater. Infant.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health and nutrition in public and private schools in the city of Recife

Bezerra

Carvalho

Oliveira

et al. 2017

Rev. Bras. Saude Mater. Infant.

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“…PAF for other countries ranged from 43% for Australia to 8% for China, depending on obesity prevalence. Silverwood et al (27) estimated PAF for knee OA in the UK at 25%, whereas Kearns et al (28) found PAF for any OA in Ireland to be 20%. Estimates of PAF may vary due to differences in the relative risk of OA for a unit change in BMI across published studies.…”

Section: Discussionmentioning

confidence: 99%

Effects of Reductions in Body Mass Index on the Future Osteoarthritis Burden in Canada: A Population‐Based Microsimulation Study

Kopeć

Sayre

Finès

et al. 2016

Arthritis Care & Research

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Objective. Osteoarthritis (OA) is the most common joint disease and a major cause of disability. Incidence and prevalence of OA are expected to increase due to population aging and increased levels of obesity. The purpose of this study was to project the effect of hypothetical interventions that change the distribution of body mass index (BMI) on OA burden in Canada. Methods. We used a microsimulation computer model of OA based on the Population Health Model platform. The model used demographic predictions for Canada and population data from an administrative database in British Columbia and national Canadian surveys.Results. Under the base-case scenario, between 2010 and 2030, OA prevalence is expected to increase from 11.5% to 15.6% in men and 16.3% to 21.1% in women. In scenarios assuming, on average, a 0.3-, 0.5-, or 1-unit drop in BMI per year, OA prevalence in 2030 would reach 14.9%, 14.6%, and 14.2% in men and 20.3%, 19.7%, and 18.5%, in women, respectively. Under these scenarios, the proportion of new cases prevented would be 9.5%, 13.2%, and 16.7%, respectively, in men, and 9.1%, 15.2%, and 25.0% in women. Targeting only those people ages ‡50 years for weight reduction would achieve approximately 70% of the impact of a full population strategy. Targeting only the obese (BMI ‡30) would likely result in a larger benefit for men than women. Conclusion. Due to the aging of the population, OA will remain a major and growing health issue in Canada over the next 2 decades, regardless of the course of the obesity epidemic.

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From obesity to cancer: a review on proposed mechanisms

Tahergorabi

Khazaei

Moodi

et al. 2016

Cell Biochemistry & Function

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Nowadays, obesity is considered as a serious and growing global health problem. It is documented that the overweight and obesity are major risk factors for a series of noncommunicable diseases, and in recent years, the obesity-cancer link has received much attention. Numerous epidemiological studies have shown that obesity is associated with increased risk of several cancer types, including colon, breast, endometrium, liver, kidney, esophagus, gastric, pancreatic, gallbladder, and leukemia, and can also lead to poorer treatment. We review here the epidemiological and experimental evidences for the association between obesity and cancer. Specifically, we discuss potential mechanisms focusing how dysfunctional angiogenesis, chronic inflammation, interaction of proinflammatory cytokines, endocrine hormones, and adipokines including leptin, adiponectin insulin, growth factors, estrogen, and progesterone and strikingly, cell metabolism alteration in obesity participate in tumor development and progression, resistance to chemotherapy, and targeted therapies such as antiangiogenic and immune therapies.

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Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level

Cited by 182 publications

References 27 publications

Health and nutrition in public and private schools in the city of Recife

Health and nutrition in public and private schools in the city of Recife

Effects of Reductions in Body Mass Index on the Future Osteoarthritis Burden in Canada: A Population‐Based Microsimulation Study

From obesity to cancer: a review on proposed mechanisms

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