Chronic desquamative gingivitis: A reconsideration

McCarthy, Francis P.; McCarthy, Philip L.; Shklar, Gerald

doi:10.1016/0030-4220(60)90292-9

Cited by 49 publications

(43 citation statements)

References 10 publications

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“…Erosive (including bullous) lesions and atrophic (erythematous) lesions are distinct forms that are usually a source of pain and discomfort. Desquamative gingivitis, a clinically descriptive term that encompasses many diseases, can apply to conditions characterized by clinically atrophic lesions with histologic oral lichen planus (McCarthy et a/., 1960;Rogers et al, 1982).…”

Section: Introductionmentioning

confidence: 99%

The Therapy of Oral Lichen Planus

Eisen

1993

Critical Reviews in Oral Biology & Medicine

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Oral lichen planus is a chronic mucocutaneous disease that is relatively common. Although many patients are asymptomatic and require no therapy, those who exhibit atrophic and erosive lesions are often a challenge to treat. All therapies are palliative, and none is effective universally. Currently employed treatment modalities include corticosteroids administered topically, intralesionally, or systemically. Alternative therapies include topical and systemic retinoids, griseofulvin, Cyclosporine, and surgery. Other medical treatments and experimental modalities, including mouth PUVA, have been reported to be effective. Controversy concerning the efficacy of all these treatments suggests that oral lichen planus is a heterogeneous disorder. Eliminating lichenoid drug eruptions, candidiasis, trauma, contact mucositis, and emotional stress may play a role in the management of these patients. This article is a review of the many treatments and measures that have been employed in the management of patients with oral lichen planus.

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Section: Introductionmentioning

confidence: 99%

The Therapy of Oral Lichen Planus

Eisen

1993

Critical Reviews in Oral Biology & Medicine

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“…As with OLP, 20% of the cases with clinical diagnosis of MMP did not correlate with the direct IF findings. In the older literature, MMP was reported as the most common condition presenting as DG 23‐25,27,28 . However, the recent studies 4,2 have shown that OLP is the most common disease associated with DG.…”

Section: Discussionmentioning

confidence: 99%

“…The mean age of onset and predilection to middle‐aged females were consistent with the literature. Pemphigus was seen in 2% of the cases, with a mean age at presentation of 58 years 24,25 …”

Section: Discussionmentioning

confidence: 99%

Definitive and Differential Diagnosis of Desquamative Gingivitis Through Direct Immunofluorescence Studies

Suresh

Neiders

2012

Journal of Periodontology

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This study has the largest cohort of patients with DG suspected of VBD reported in the literature. The patients were predominantly females who had most often been seen by a periodontist. The definitive diagnosis of DG was most accurately achieved when H & E along with two biopsies for direct IF studies were submitted for testing. H & E studies were particularly important for definitive diagnosis of negative cases. Oral lichen planus was the most common disease presenting as DG, which is consistent with recent studies. Systemic connective tissue disorders that present as DG at initial clinical examination require direct IF and serum studies for a conclusive diagnosis. Clinical pathologic correlation, including history, presentation, H & E, and direct IF studies, are essential in establishing a definitive and differential diagnosis for cases presenting with DG.

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“…3 Therefore proper diagnosis of the underlying pathologic entity must be established in order to provide the appropriate patient care. Furthermore, symptomatology of desquamative gingivitis can be aggravated by the concurrent presence of dental plaque.…”

Section: Discussionmentioning

confidence: 99%