Chronic Cutaneous Infection Caused by Mycobacterium intracellulare

Cutaneous manifestations of infection by nontuberculous mycobacteria

“…The prevalence of MAC disease has increased since the onset of the AIDS epidemic; it is now the commonest NTM isolated from such patients. 26 MAC are also ubiquitous in the environment, 27 but cutaneous infection due to MAC are unusual; when it does occur, there are variable appearances such as multiple ulcers, 28 abscesses, 29 painless nodules, plaques resembling lepromatous leprosy, 30 ecthyma-like lesions, prurigo nodularis-like lesions, 31 erythematous masses with matted lymph nodes 32 and rosacea-like lesions, 33 all predominantly in immunosuppressed patients. [33][34][35] Disseminated disease is also associated with such immunosuppression, and on rare occasions cutaneous lesions may also be present.…”

A Pediatric Case of Atypical Mycobacterium avium Infection of the Skin

“…The patients comprised 12 males and 17 females ranging in age from 2 to 79 years. The symptoms consisted of indurations and subcutaneous abscesses resembling those of scrofuloderma in nine cases (3,(5)(6)(7)22,23), ulceration in 5 cases (2,14,17,19,21), lesions similar to those of lupus vulgaris in 3 cases (4,8,26), and multiple intradermal or subcutaneous nodules in 10 cases (9-13, 15, 16, 18). Of the total of 29 cases, there were four (2,23) in whom the lesions appeared as a complication of AIDS, four (10,11,20,22) in whom lesions developed during long-term administration of corticosteroids for diseases such as systemic lupus erythematosus, two that were complications of diabetes mellitus (17,21), one that was treated by radiotherapy (26), and 17 cases in which neither the presence of a disease nor the administration of a drug likely to cause immunosuppression was a factor.…”

“…The 29 cases in Table 1 that were reported before ours included 12 in which the pathogen was recognized in the tissues. The staining methods used were the Ziehl-Neelsen technique in seven cases (5,8,11,13,15,26), fluorescent staining in two cases (19,21), and the Fite method in one (20). In two cases (2), the technique was not reported.…”

“…However, not many reports of atypical Mycobacterium aoium complex infections in which lesions are found only in the skin have appeared in the literature. They include only 17 cases in Japan (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) and 11 in other countries (2,(19)(20)(21)(22)(23)(24)(25)(26). This report presents a case of cutaneous atypical mycobacteriosis due to Mycobacterium auium in an otherwise healthy 12-year-old girl and reviews previous cases of cutaneous atypical Mycobacterium aoium complex infection.…”

Tuberculosis of the Skin

“…Post-traumatic inoculation of the skin is rare and may cause purulent leg ulcers, folliculitis, ulcerated nodules, panniculitis, abscesses, or even scaly nondescript plaques (Cox and Stransbough 1981). More commonly, the cutaneous involvement is secondary to disseminated disease with clinical presentation similar to the primary infection but more generalized and severe.…”