Chronic Coronary Artery Disease: Diagnosis and Management

2013 Esc Guidelines on the Management of Stable Coronary Artery Disease

“…В отличие от этого, недавние рандомизированные исследова-ния, в которых сравнивали систематическое раннее проведение ЧКВ с консервативной стратегией, управляемой в зависимости от ишемии, продемон-стрировали благоприятные тенденции для раннего ЧКВ, с достоверным снижением смертности или ИМ по данным мета-анализа [440][441]. В целом, реваскуляризация улучшает выживае-мость у "более больных" пациентов, особенно при наличии дисфункции ЛЖ [442][443][444][445][446][447]. С самого начала использования коронарной ангиографии возникло широкое признание того, что дисфункция ЛЖ -один из наиболее сильных показателей (предикто-ров) неблагоприятного прогноза [448].…”

Efficacy and safety of ivabradine as an add-on to atenolol in patients with chronic stable ischemic heart disease

“…1 Angina pectoris is characterized by substernal discomfort, heaviness, or a pressure-like feeling, which may radiate to the jaw, shoulder, back, or arm and which typically lasts several minutes. 2 Angina pectoris is caused by myocardial ischemia due to an imbalance between myocardial oxygen requirements and myocardial oxygen supply. The former may be elevated by increase in heart rate and contractility, the latter is determined by coronary blood flow and coronary arterial oxygen content.…”

“…Ivabradine reduces the slope of diastolic depolarization in these cells and lowers the heart rate at rest and during exercise. 2,9 Beta blockers, unlike ivabradine, reduce I f activation by decreasing the sympathetic activity and cAMP formation, resulting in a lower HR. Left ventricular function and ventricular remodelling may be improved with I f inhibition with beta blockers like atenolol.…”

Magnetocardiography in Unshielded Setting: Heart Electrical Image Based on 2-D and 3-D Data in Comparison with Perfusion Image Based on PET Results – Clinical Cases

“…Moreover, in the developing world, particularly in Ukraine, prevalence of CAD is even higher and there is the tendency tends to affect people at a younger age and thus could negatively affect the workforce and economic productivity. The morbidity, mortality, and socioeconomic importance of CAD make its diagnosis and management fundamental for all practicing physicians (Cassar et al, 2009). …”