2020
DOI: 10.1590/1678-5150-pvb-6526
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Chronic copper poisoning in beef cattle in the state of Mato Grosso, Brazil

Abstract: Copper is an essential micromineral in animal feed; however, when consumed in excess, it can cause liver necrosis, hemolytic crisis, hemoglobinuric nephrosis and death in cattle. Although uncommon in this species, copper poisoning occurs as a result of exacerbated supplementation, deficiency of antagonist microminerals, or previous liver lesions. An outbreak of chronic copper poisoning is reported in semi-confined cattle after supplementation with 50 mg/Kg of dry matter copper. The cattle showed clinical signs… Show more

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Cited by 3 publications
(3 citation statements)
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References 52 publications
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“…poisoning. Also, copper poisoning in cattle is associated with copper supplementation, which was not performed in the animals of this study, and have lesions related to intravascular hemolysis, a feature not present in the current cases (Martins et al 2020). Thus, L. camara L. poisoning must be considered as a differential diagnosis in cases of acute necrotic hepatopathy in cattle, despite the absence of photosensitization.…”
Section: Discussionmentioning
confidence: 68%
“…poisoning. Also, copper poisoning in cattle is associated with copper supplementation, which was not performed in the animals of this study, and have lesions related to intravascular hemolysis, a feature not present in the current cases (Martins et al 2020). Thus, L. camara L. poisoning must be considered as a differential diagnosis in cases of acute necrotic hepatopathy in cattle, despite the absence of photosensitization.…”
Section: Discussionmentioning
confidence: 68%
“…Research on the impacts of heavy metals exposure on the health, reproductive, and productive performance of livestock has garnered significant attention in recent years. Several published reviews have explored the diverse effects of heavy metals such as Pb, Cd, Hg, and As on various aspects of livestock physiology and productivity ( Martinez et al, 2020 ; Sun et al, 2022 ; Duffy et al, 2023 ; Sadeghian et al, 2024 ). These reviews have elucidated the mechanisms by which heavy metals enter the animal body, their accumulation in tissues, and the resultant adverse effects on health.…”
Section: Introductionmentioning
confidence: 99%
“…Toxic levels in liver and kidneys are >250 ppm and 10 ppm in cattle, and >250 ppm and >18 ppm in sheep ( Lopez-Alonso et al, 2006 ; Dalefield, 2017 ). Treatment involves using Mo and chelating agents ( Antonelli et al, 2016 ; Mecitoglu et al, 2017 ; Martins et al, 2020 ). Zn supplementation is effective in preventing excessive Cu accumulation in sheep ( Minervino et al, 2009 ).…”
Section: Introductionmentioning
confidence: 99%