Chronic coffee consumption in the diet-induced obese rat: impact on gut microbiota and serum metabolomics

Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: a randomised feasibility trial

“…*p<0.05, **p<0.01, ***p<0.001 the amino acid profile [12], or altered rates of colonic fermentation with production of short-chain FA [29]. Chronic coffee consumption has been reported to have similar effects [30]. On the other hand, coffee can impair insulin sensitivity, while liver steatosis and inflammation is reduced, despite identical and unchanged body weight in spontaneously diabetic mice [31].…”

Alzheimer’s disease and gut microbiota

“…Firstly, gut microbiota can easily digest the fiber in coffee beans and harvest its energy to help their own growth. Simultaneously, they can reduce the ratio of Firmicutes to Bacteroidetes bacteria and this alteration in Firmicutes to Bacteroidetes ratio is associated with reduced inflammation (Cowan et al, 2014). Secondly, the capacity of body to utilize coffee polyphenols is also influenced by gut microbiota in a large extent.…”

Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats

“…The 16S ribosomal RNA (rRNA) gene copies value was calculated according the following webpage: http:// cels.uri.edu/gsc/cndna.html using average genome sizes. Standard curves were normalized to the copy number of the 16S rRNA gene obtained from the following webpage: http:// rrndb.umms.med.umich.edu/ according to previous work[16,36,37]. The percent Firmicutes was calculated as the sum total of all Firmicutes (Clostridium coccoides, Clostridium leptum, Clostridium cluster XI, Clostridium cluster I, Roseburia species, and Lactobacillus species) divided by total bacteria.…”