Chronic actinic damage of facial skin

Bilaç, Cemal; Şahin, Mustafa Turhan; Öztürkcan, Serap

doi:10.1016/j.clindermatol.2014.02.014

Cited by 27 publications

(17 citation statements)

References 51 publications

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“…The changes in pigmentation during pregnancy are mostly physiological; and bioactive molecules released from estrogen, progesterone and placenta are known to play a role in this process. The increase in pigmentation progresses during pregnancy, but it is expected that the skin will return to its original appearance after pregnancy [1,2]. Melasma (chloasma or the mask of pregnancy) describes gray-brown hypermelanosis on the face and rarely on the neck and forearms, which are well-circumscribed, symmetrical and tend to unite.…”

Section: Severe Melasma Image Presentationmentioning

confidence: 99%

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Severe melasma image presentation

Özturk¹

2019

Ann Clin Anal Med

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Section: Severe Melasma Image Presentationmentioning

confidence: 99%

“…Due to being a cosmetic problem, it can lead to emotional changes. Maxillary melasma constitutes one-fifth of all types of melasma [1,2]. A 25-year-old woman in her 39th week of pregnancy presented with complaint of discoloration on her face.…”

Section: Severe Melasma Image Presentationmentioning

confidence: 99%

Severe melasma image presentation

Özturk¹

2019

Ann Clin Anal Med

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“…Excessive UVR exposure has been associated with short-term harmful outcomes such as sunburn (erythema) and photo-immunosuppression [2], but also with long-term consequences such as actinic damage (e.g. actinic keratosis) [3,4], photo-ageing [5] and skin cancer [6,7].…”

Section: Introductionmentioning

confidence: 99%

Prospective Evaluation of the Efficacy of a Food Supplement in Increasing Photoprotection and Improving Selective Markers Related to Skin Photo-Ageing

Granger

Aladren

Delgado

et al. 2019

Dermatol Ther (Heidelb)

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Introduction: Skin exposure to ultraviolet radiation (UVR) can cause oxidative stress, particularly in the absence of adequate protective measures or in individuals with a sensitive skin type. Most commonly, protection from UVR entails the use of topical sunscreens. Sunscreens, however, have various limitations. The objective of this study was to evaluate the efficacy and tolerability of an oral food supplement containing a combination of actives with mainly antioxidative properties (vitamins A, C, D3, E, selenium, lycopene, lutein, as well as green tea, polypodium and grape extracts) in the context of photoprotection.

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“…Photoaged skin is characterized by wrinkles, mottled pigmentation, telangiectasia, and malignancies that can develop in chronically sunexposed skin (Bilac, Sahin, & Ozturkcan, 2014). Mottled hyperpigmentation is of great concern to patients with photoaged skin.…”

Section: Introductionmentioning

confidence: 99%

Photodynamic therapy inhibits melanogenesis through paracrine effects by keratinocytes and fibroblasts

Kim

Park

et al. 2017

Pigment Cell Melanoma Res

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Photodynamic therapy (PDT) is a treatment option for skin cancer and premalignant skin diseases and exhibits rejuvenation effects, including reducing fine wrinkles and whitening, on aged skin. In this study, we investigated the mechanism underlying the whitening effects of PDT on melanocytes (MCs) in vitro and in vivo. Exposure of MCs to PDT in vitro reduced their melanin content and tyrosinase activity without, however, affecting cell survival. Interestingly, melanogenesis was also inhibited by exposing MCs to conditioned media of PDT-treated keratinocytes or dermal fibroblasts. This paracrine effect was likely due to a decreased release of melanocyte-stimulating cytokines such as Kit ligand and hepatocyte growth factor from these cells. Furthermore, we observed that PDT reduced mottled hyperpigmentation of photoaged patient skin in vivo, highlighting the clinical importance of skin whitening by PDT.

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Chronic actinic damage of facial skin

Cited by 27 publications

References 51 publications

Severe melasma image presentation

Severe melasma image presentation

Prospective Evaluation of the Efficacy of a Food Supplement in Increasing Photoprotection and Improving Selective Markers Related to Skin Photo-Ageing

Photodynamic therapy inhibits melanogenesis through paracrine effects by keratinocytes and fibroblasts

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