Chromosome numbers in the genus Mentha L.

Harley, R. M.; Brighton, C. A.

doi:10.1111/j.1095-8339.1977.tb01168.x

Cited by 118 publications

(99 citation statements)

References 14 publications

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“…In spite of the significant differences in essential oil chemistry, the observation that both dehydrogenases of peppermint and spearmint appear to utilize (2)-trans-carveol and (2)-trans-isopiperitenol as substrates (Croteau et al, 1991), and the facts that spearmint is a parent of peppermint (Murray et al, 1972;Harley and Brighton, 1977) and that other genes of the two species are very similar (Lupien et al, 1999), suggested that the target monoterpenol dehydrogenases would also be very similar. Polyclonal antibodies prepared against the peppermint ISPD ( Turner and Croteau, 2004) were used for immunoblotting of secretory cell extracts.…”

Section: Immunodetection Of Carveol Dehydrogenasementioning

confidence: 99%

“…Thus, the oxidation of the initially formed monoterpenol is the only common redox step in monoterpene metabolism of these two Mentha species. The monoterpenol dehydrogenases of spearmint, peppermint, and scotch spearmint (Mentha x gentiles) all appear capable of utilizing both (2)-trans-carveol and (2)-trans-isopiperitenol as a substrate, an observation perhaps not surprising because spearmint is a parent of both peppermint and scotch spearmint (Harley and Brighton, 1977).…”

mentioning

confidence: 98%

“…The essential oils of both peppermint (Mentha x piperita), a sterile cross between Mentha spicata and Mentha aquatica (Murray et al, 1972;Harley and Brighton, 1977), and spearmint (Mentha spicata) consist primarily of monoterpenes (Lawrence, 1981) that are distinguished by the position of oxygenation on the p-menthane ring conferred by two distinct regiospecific cytochrome P450 limonene hydroxylases (Fig. 1).…”

mentioning

confidence: 99%

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Monoterpene Metabolism. Cloning, Expression, and Characterization of (−)-Isopiperitenol/(−)-Carveol Dehydrogenase of Peppermint and Spearmint

2005

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The essential oils of peppermint (Mentha x piperita) and spearmint (Mentha spicata) are distinguished by the oxygenation position on the p-menthane ring of the constitutive monoterpenes that is conferred by two regiospecific cytochrome P450 limonene-3-and limonene-6-hydroxylases. Following hydroxylation of limonene, an apparently similar dehydrogenase oxidizes (2)-trans-isopiperitenol to (2)-isopiperitenone in peppermint and (2)-trans-carveol to (2)-carvone in spearmint. Random sequencing of a peppermint oil gland secretory cell cDNA library revealed a large number of clones that specified redox-type enzymes, including dehydrogenases. Full-length dehydrogenase clones were screened by functional expression in Escherichia coli using a recently developed in situ assay. A single full-length acquisition encoding (2)-trans-isopiperitenol dehydrogenase (ISPD) was isolated. The (2)-ISPD cDNA has an open reading frame of 795 bp that encodes a 265-residue enzyme with a calculated molecular mass of 27,191. Nondegenerate primers were designed based on the (2)-trans-ISPD cDNA sequence and employed to screen a spearmint oil gland secretory cell cDNA library from which a 5#-truncated cDNA encoding the spearmint homolog, (2)-trans-carveol-dehydrogenase, was isolated. Reverse transcription-PCR amplification and RACE were used to acquire the remaining 5#-sequence from RNA isolated from oil gland secretory cells of spearmint leaf. The fulllength spearmint dehydrogenase shares .99% amino acid identity with its peppermint homolog and both dehydrogenases are capable of utilizing (2)-trans-isopiperitenol and (2)-trans-carveol. These isopiperitenol/carveol dehydrogenases are members of the short-chain dehydrogenase/reductase superfamily and are related to other plant short-chain dehydrogenases/ reductases involved in secondary metabolism (lignan biosynthesis), stress responses, and phytosteroid biosynthesis, but they are quite dissimilar (approximately 13% identity) to the monoterpene reductases of mint involved in (2)-menthol biosynthesis. The isolation of the genes specifying redox enzymes of monoterpene biosynthesis in mint indicates that these genes arose from different ancestors and not by simple duplication and differentiation of a common progenitor, as might have been anticipated based on the common reaction chemistry and structural similarity of the substrate monoterpenes.Monoterpenes, the C 10 members of the terpenoid family of secondary metabolites, are largely responsible for the fragrance and flavor characteristics of plants and are well known as components of plant essential oils (Parry, 1969). The essential oils of both peppermint (Mentha x piperita), a sterile cross between Mentha spicata and Mentha aquatica (Murray et al., 1972;Harley and Brighton, 1977), and spearmint (Mentha spicata) consist primarily of monoterpenes (Lawrence, 1981) that are distinguished by the position of oxygenation on the p-menthane ring conferred by two distinct regiospecific cytochrome P450 limonene hydroxylases (Fig. 1). Thus, following cycliz...

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Section: Immunodetection Of Carveol Dehydrogenasementioning

confidence: 99%

mentioning

confidence: 98%

mentioning

confidence: 99%

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Monoterpene Metabolism. Cloning, Expression, and Characterization of (−)-Isopiperitenol/(−)-Carveol Dehydrogenase of Peppermint and Spearmint

2005

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“…"The wild mint (Mentha longifolia L. (Lamiaceae)) grows extensively in different part of Iran and other regions such as Mediterranean, Europe, Australia, and North Africa" [1].…”

Section: Introductionmentioning

confidence: 99%

Determination of Safety Margin for Hepatotoxic Effect of Mentha Longifolia Essential Oil in Rat

Hesami

Sajjadi

Hosseini-Sharifabad

2017

IJT

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“…Dentre as 25 espécies de Mentha (Lamiaceae), destaca-se Mentha x gracilis Sole, um complexo híbrido originado de M. arvensis L. e M. spicata L. (HARLEY & BRIGHTON, 1977), que, através de uma série de cruzamentos, produz indivíduos estéreis e vários quimiotipos, todos com óleos essenciais ricos em monoterpenos. A composição química dos óleos essenciais pode variar conforme os I Programa de Pós-graduação em Agronomia (PPGA), Universidade Federal de Santa Maria (UFSM), Núcleo de Pesquisas em Ecofisiologia e Hidroponia (NUPECH), 97015-900, Santa Maria, RS, Brasil.…”

Section: Introductionunclassified

Produção e qualidade do óleo essencial de menta em hidroponia com doses de potássio

et al. 2007

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Chromosome numbers in the genus Mentha L.

Cited by 118 publications

References 14 publications

Monoterpene Metabolism. Cloning, Expression, and Characterization of (−)-Isopiperitenol/(−)-Carveol Dehydrogenase of Peppermint and Spearmint

Monoterpene Metabolism. Cloning, Expression, and Characterization of (−)-Isopiperitenol/(−)-Carveol Dehydrogenase of Peppermint and Spearmint

Determination of Safety Margin for Hepatotoxic Effect of Mentha Longifolia Essential Oil in Rat

Produção e qualidade do óleo essencial de menta em hidroponia com doses de potássio

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