Chromoblastomycosis in India

Sharma, Nand Lal; Sharma, Ramesh C.; Grover, Prem Singh; Gupta, Manohar Lal; Sharma, Ashok Kumar; Mahajan, Vikram K.

doi:10.1046/j.1365-4362.1999.00820.x

Cited by 48 publications

(52 citation statements)

References 3 publications

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“…Therefore, patients very often seek medical care years or decades after acquiring the infection or developing the skin lesion [6]. Early lesions start as an ulcer, nodule, or papule, and slowly progress to form plaques with verrucous appearance over years [7].…”

Section: Discussionmentioning

confidence: 99%

Chromoblastomycosis due to Fonsecaea pedrosoi: an old wine in a rare bottle

Khan

Kumar

Vinod

et al. 2015

J Infect Dev Ctries

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Chromoblastomycosis is a chronic subcutaneous mycosis commonly caused by Fonsecaea, Phialophora, and Cladophialophora spp. Out of these, Fonsecaea pedrosoi is the most common etiological agent, implicated in 70%-90% of the cases reported worldwide. The histopathological diagnosis of chromoblastomycosis is based on visualization of medlar or sclerotic bodies in the tissue. These sclerotic bodies divide by planar division. Rarely, budding is seen in these sclerotic bodies. As this entity can be confused with phaeohyphomycosis, it is important to be aware of such a presentation also. We report two cases of chromoblastomycosis that showed budding sclerotic bodies.

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Section: Discussionmentioning

confidence: 99%

Chromoblastomycosis due to Fonsecaea pedrosoi: an old wine in a rare bottle

Khan

Kumar

Vinod

et al. 2015

J Infect Dev Ctries

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“…Unusual sites of infection such as the genitalia and nose have also been reported. 5 Chromoblastomycosis is characteristically slow to develop. Early lesions may resemble a dermatophyte infection or begin as a papule.…”

Section: Introductionmentioning

confidence: 99%

“…Chromoblastomycosis remains confined to the subcutaneous fat and does not invade underlying muscle or bone except in cases of immunosuppression. 2,6 Extracutaneous haematogenous dissemination to regional lymph nodes, lungs and brain has rarely been reported, 5 although some authors believe that these cases may actually represent phaeohyphomycosis. 7 The principal differential diagnosis of verrucous-like lesions of chromoblastomycosis includes verrucous variants of leishmaniasis and tuberculosis, sporotrichosis and verrucous carcinoma.…”

Section: Introductionmentioning

confidence: 99%

Chromoblastomycosis: clinical presentation and management

Ameen¹

2009

Clinical and Experimental Dermatology

120

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“…Chromoblastomycosis is belong to phaeohypomycosis group and caused by dematiaceous (naturally pigmented) fungi such as Fonsecaea pedrosoi, Phialophora verrucosa, Fonsecaea compactum, Cladophialophora carrionii, exophiala jeanselmei, e. castellanii and Rhinocladiella aquaspersa. Fonsecaea pedrosoi is the most common causative agent of this condition (1,7).…”

Section: Discussionmentioning

confidence: 99%

Cutaneous chromoblastomycosis mimicking tuberculosis verrucosa cutis: look for copper pennies!

Bandyopadhyay¹,

Majumdar²,

Gangopadhyay³

et al. 2013

TJPATH

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Chromoblastomycosis is a rare chronic fungal infection of skin and subcutaneous tissue. It is primarily a disease of tropical and subtropical regions and affects mainly the agricultural workers following trauma with vegetable matter. Cutaneous Chromoblastomycosis may clinically mimic cutaneous tuberculosis as both the condition usually presents with hyper pigmented verrucous lesion of skin.Here in we report a case of chronic cutaneous Chromoblastomycosis in a middle aged woman from north eastern part of India, who was initially misdiagnosed as tuberculosis verrucosa cutis. In histopathology characteristic brown colored spores of the fungus (also known as copper pennies) were seen within dermal abscess. The organism isolated from culture of the biopsy material was Fonsecaea pedrosoi thus confirming our diagnosis of cutaneous chromoblastomycosis. The patient responded well to oral Itraconazole.The dermatologists and pathologists should be aware of this condition especially when dealing with verrucous lesion of the skin. The pathologists should search for fungal spores in cutaneous lesion with pseudoepitheliomatous hyperplasia and dermal abscess.

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Chromoblastomycosis in India

Abstract: Combination therapy with two azoles was attempted with some success for clinical cure.

Cited by 48 publications

References 3 publications

Chromoblastomycosis due to Fonsecaea pedrosoi: an old wine in a rare bottle

Chromoblastomycosis due to Fonsecaea pedrosoi: an old wine in a rare bottle

Chromoblastomycosis: clinical presentation and management

Cutaneous chromoblastomycosis mimicking tuberculosis verrucosa cutis: look for copper pennies!

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