Masses of the cavernous sinus and Meckel's cave are uncommon. We report a patient who presented with facial pain. His exam at the most recent presentation was normal other than a diminished corneal reflex on the right side and hyperreflexia throughout. Imaging demonstrated an enhancing lesion of the left occipital lobe, left gyrus rectus, right ventricular trigone, right cavernous sinus and Meckel's cave, and diffuse intracranial meningeal enhancement. The histopathological examination and clinical course of this patient are discussed.
Masses of the cavernous sinus and Meckel's cave are uncommon. We report a patient who presented with facial pain. His exam at the most recent presentation was normal other than a diminished corneal reflex on the right side and hyperreflexia throughout. Imaging demonstrated an enhancing lesion of the left occipital lobe, left gyrus rectus, right ventricular trigone, right cavernous sinus and Meckel's cave, and diffuse intracranial meningeal enhancement. The histopathological examination and clinical course of this patient are discussed.
A 3-year-male child was operated for 4th ventricular choroid plexus carcinoma. He presented with features of raised intracranial pressure and midline posterior fossa syndrome. A total excision of tumor could be achieved as there was no parenchymal invasion or adherence with the walls of 4th ventricle. Cerebrospinal fluid pathway was reestablished and hydrocephalus resolved gradually. The child developed peritoneal and liver metastases at follow-up of 14-month without local recurrence. A choroid plexus carcinoma metastasizes to the liver and peritoneum.
Choroid plexus tumor (CPT) is a primary intracranial neoplasm of the choroid plexus epithelium in the central nervous system. In the current World Health Organization classification, CPT is classified into two categories; choroid plexus papilloma (CPP) and carcinoma (CPC). In the present study, we investigated immunohistochemical expressions of N-cadherin, E-cadherin and β-catenin in 5 canine CPT cases (1 disseminated CPC, 2 CPCs and 2 CPPs). One CPP case was positive for N-cadherin and β-catenin, but negative for E-cadherin. The disseminated CPC case was positive for E-cadherin and β-catenin, but negative for N-cadherin. The other cases were positive for the three molecules examined. These results suggest that loss of the N-cadherin expression might associate with the spreading of CPC cells.
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