Choroid plexus carcinoma: A case report and literature review

Abstract

Choroid plexus carcinoma is a rare tumor representing less than 1% of all brain tumors. In adult, the incidence is extremely rare making the diagnosis difficult. Majority of choroid plexus tumor is found in the ventricle. However, ectopic sites such as intracranial extraventricular or spine have been reported. We report a case of choroid plexus carcinoma in a 39-year-old man. The clinical presentation, pathology and management are discussed.

Cerebellopontine Angle Primary Choroid Plexus Carcinoma Present in an Adult: Case Report and Literature Review

“…Presentation with multiple CPCs is rare, occurring in only 5% of CPC patients [9]. Metastatic lesions have a higher frequency of being supratentorial [10]. Our patient uniquely presented with a primary CPC in the atrium of the left ventricle and ectopic in the CPA without any invasion from the fourth ventricle.…”

“…Ectopic sites are not commonly reported but include the suprasellar region, foramen magnum, and spinal canal in the absence of other intracranial lesions [10]. Ectopic CPC is thought to arise through CSF dissemination [10]. Our literature search found only two occurrences of cerebellopontine angle CPCs; both had an invasion of CPC from the fourth ventricle through the foramen of Luschka into the CPA [11][12].…”

“…Our literature search found only two occurrences of cerebellopontine angle CPCs; both had an invasion of CPC from the fourth ventricle through the foramen of Luschka into the CPA [11][12]. The most common site for adults is in the fourth ventricle (63%) while in the pediatric group is the lateral ventricle (72%) [10]. Presentation with multiple CPCs is rare, occurring in only 5% of CPC patients [9].…”

“…CPCs are typically intraventricular, however, extraventricular tumors have been reported [7][8][9]. Ectopic sites are not commonly reported but include the suprasellar region, foramen magnum, and spinal canal in the absence of other intracranial lesions [10]. Ectopic CPC is thought to arise through CSF dissemination [10].…”