Chordoma: radiologic evaluation of 20 cases

Firooznia, Hossein; Pinto, RS; Lin, J. P.; Baruch, HH; Zausner, Joseph

doi:10.2214/ajr.127.5.797

Cited by 91 publications

(36 citation statements)

References 17 publications

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“…More recently, Heffelfinger, et al, 7 reviewed 36 cases of non-chondroid chordoma in these regions; the mean survival times were 5.2, 4.8, 1.8, and 0.9 years, respectively, for radiation plus surgery, radiation, surgery, or no treatment. Firooznia,et al,6 reported that two of nine patients with such tumors were free of disease 2.5 and 6 years after treatment. Only one of 15 patients treated for sphenoid or vertebral chordoma at Memorial Hospital survived without evidence of disease, s However, an occasional patient will survive a long time following biopsy and conventional radiation treatmenP or without treatment.…”

Section: Discussionmentioning

confidence: 99%

Definitive radiation therapy for chordoma and chondrosarcoma of base of skull and cervical spine

Suit¹,

Goitein²,

Munzenrider³

et al. 1982

Journal of Neurosurgery

210

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Proton-beam radiation therapy has been developed for the treatment of chordomas or sarcomas of bone or soft tissue that abut the central nervous system. The authors report the results of treatment of 10 patients, six with chordoma, three with chondrosarcoma, and one with a neurofibrosarcoma. Local control has been achieved for all patients (with, however, one marginal failure) with a follow-up period ranging from 2 months to 6 years. High doses of radiation, up to 76 Cobalt Gray Equivalents (CGE), have been delivered without significant morbidity. In particular, no neurological sequelae have been observed.

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Section: Discussionmentioning

confidence: 99%

Definitive radiation therapy for chordoma and chondrosarcoma of base of skull and cervical spine

Suit¹,

Goitein²,

Munzenrider³

et al. 1982

Journal of Neurosurgery

210

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“…Tumors in infants and children are rare, and show more malignant behavior and distant metastasis [3]. Pathologically, cellular pleomorphism Radiographic hallmarks of chordomas are: (a) their midline location within the skull base or spinal column, (b) destruction of one or more vertebrae and involvement of intervertebral discs, (c) soft tissue mass formation in paraspinal regions, and (d) calcifications within the lesion [4,5]. Our patient did not show any of these radiographic features.…”

Section: Discussionmentioning

confidence: 52%

Epidural dumbbell-shaped chordoma mimicking a neurinoma

et al. 1996

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“…13,20 Radiodensities are frequently present and are thought to represent remaining fragments of the destroyed clivus rather than new matrix formation. 13,21 At MRI, they are usually hypo-to isointense on T1-weighted imaging, with cystic components that may contain protein or haemorrhage, giving them a bright signal on T1-weighted images. 22 On T2-weighted images, they are characteristically of high signal.…”

Section: Clinical Presentationsmentioning

confidence: 99%