Chondroblastoma: A clinical and radiological study of 104 cases

Abstract

The clinical and radiographic findings in 104 patients with chondroblastoma are presented. Pain was an almost constant presenting complaint, often accompanied in the case of para-articular lesions by impaired function of an adjacent joint. The majority (80%) were in long bones with a mean age of presentation of 16 years. The characteristic radiological image of these lesions was an eccentric radiolucency, having a sharply defined sclerotic margin and containing areas of calcification in approximately a third of cases. They were always related to a growth plate. Nearly half were confined to the affected epiphysis or apophysis itself, but most of the remainder had traversed the growth plate to involve also the adjacent metaphysis. The bones around the knee and the proximal ends of the humerus and femur were the sites of predilection. A minority (20%) affected flat bones and short tubular bones of the hand and foot, with a peculiar affinity for the calcaneus and talus. The mean age of presentation of these was 28 years. The radiological pattern was similar, except for a greater tendency to expand the affected bone. Complications included the formation of a secondary aneurysmal bone cyst in 16 cases (10 of them in long bones), one malignant chondroblastoma, and one fibrosarcoma developing after radiation of the original chondroblastoma.

Primary Osseous Tumors of the Hindfoot: Why the Delay in Diagnosis and Should We Be Concerned?

“…The talus was a rare location accounting for just 8% of benign lesions and none that were malignant [16]. The existing literature is limited: there have been two location-specific small case series of calcaneus and talus, respectively [4,10], three case series of osseous neoplasms of the foot [1,5,16] or the hand and foot [19], and tumor-specific review articles [3,7,8,11,13,17,18,21]. The majority comprise individual case reports describing specific osseous lesions and their treatment.…”

Chondroblastoma of thoracic vertebra in young adult causing paraparesis

“…Chondroblastoma is benign cartilaginous neoplasm that generally affects the appendicular skeleton and occurs in the second decade of life (1). It is much more common in men than in women with male to female ratio of 2:1(3, 5).…”

The assessment of clinical approaches and properties of benign hindfoot tumors

“…Radyoloji, klinik muayenenin tamamlayıcısıdır ve çoğu kez klinik muayeneden elde edilen bilgilerden daha fazlasını verir. Radyolojik muayenenin amacı, tümörü taklit edebilecek diğer patolojilerin ayırt edilmesi, tümörün doğası ve yayılımının belirlenmesi, biyopsi için uygun dokunun saptanması ve tedavinin takibidir (8,11).…”

“…Kemik tümörlü hastaya yaklaşımda bir sonraki adımın ne olacağına radyografiden elde edilen bilgilere göre karar verilir. Çoğu benign kemik tümörü ve tümör benzeri lezyonun tanısı radyografi ile konulabilir ve ek radyolojik incelemeye veya biyopsiye gerek kalmaz (8,12,13). Manyetik rezonans görüntüleme kemik tümörlerinin yayılımının belirlenmesinde en değerli yöntem kabul edilir.…”

“…Kemik metastazlarını göstermede direkt grafilere göre duyarlılığı daha yüksek olup daha ekonomiktir. Normal bir sintigrafi sonucu bir lezyonun büyük olasılıkla benign olduğunu gösterir, fakat anormal bir sintigrafi sonucu malign benign ayırımı yapamaz (8,15,16). Biyopsi değerlendirme ve evrelendirme sürecinde en son aşamadır.…”