Chondroblastoma of thoracic vertebra in young adult causing paraparesis

Giri, Pramod Janardan; Chavan, Vaibhav Sharadrao

doi:10.1515/romneu-2017-0054

Cited by 3 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A total of 61 patients with spinal CB were included, including 8 from our institution and 53 from 27 eligible studies in the literature (Supplementary material). 1 , 8 - 11 , 15 - 36 The clinicopathological characteristics of the patients are summarized in Table 1 . Overall, there were no differences in clinicopathological features between the local and literature cohorts, except for absence or presence of spinal canal invasion and chicken-wire calcification ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Clinicopathological and Prognostic Characteristics in Spinal Chondroblastomas: A Pooled Analysis of Individual Patient Data From a Single Institute and 27 Studies

Zheng

Huang

Liu

et al. 2021

Global Spine Journal

View full text Add to dashboard Cite

Study Design: Retrospective pooled analysis of individual patient data. Objectives: Spinal chondroblastoma (CB) is a very rare pathology and its clinicopathological and prognostic features remain unclear. Here, we sought to characterize the clinicopathological data of a large spinal CB cohort and determine factors affecting the local recurrence-free survival (LRFS) and overall survival (OS) of patients. Methods: Electronic searches using Medline, Embase, Google Scholar and Wanfang databases were performed to identify eligible studies per predefined criteria. A retrospective review was also conducted to include additional patients at our center. Results: Twenty-seven studies from the literature and 8 patients from our local institute were identified, yielding a total of 61 patients for analysis. Overall, there were no differences in clinicopathological characteristics between the local and literature cohorts, except for absence or presence of spinal canal invasion by tumor on imagings and chicken-wire calcification in tumor tissues. Univariate Kaplan-Meier analysis revealed that previous treatment, preoperative or postoperative neurological deficits, type of tumor resection, secondary aneurysmal bone cyst (ABC), chicken-wire calcification and radiotherapy correlated closely with LRFS, though only type of tumor resection, chicken-wire calcification and radiotherapy were predictive of outcome based on multivariate Cox analysis. Analyzing OS, we found that a history of preoperative treatment, concurrent ABC, chicken-wire calcification, type of tumor resection and adjuvant radiotherapy had a significant association with survival, whereas only type of tumor resection remained statistically significant after adjusting for other covariables. Conclusion: These data may be helpful in prognostic risk stratification and individualized therapy decision making for patients.

show abstract

Section: Resultsmentioning

confidence: 99%

Clinicopathological and Prognostic Characteristics in Spinal Chondroblastomas: A Pooled Analysis of Individual Patient Data From a Single Institute and 27 Studies

Zheng

Huang

Liu

et al. 2021

Global Spine Journal

View full text Add to dashboard Cite

show abstract

“…According to the latest World Health Organization classification, CB is classified as an intermediate tumor that is locally aggressive and rarely metastasizes (< 2%), with a local recurrence rate of up to 38% and a 2% incidence of lung metastases[ 4 ]. Spinal CB has a higher recurrence rate and more aggressive tumor growth compared to long-bone CB[ 6 , 7 ], and Vialle et al [ 8 ] and Giri and Chavan[ 9 ] even stated that the local recurrence rate is 100% when CB involves the long bones. In view of the high invasiveness and high recurrence rate of this disease, it is necessary to understand fully this disease.…”

Section: Discussionmentioning

confidence: 99%

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Zheng¹,

Niu²,

Wang³

et al. 2021

WJCC

View full text Add to dashboard Cite

BACKGROUND Chondroblastoma (CB) is an intermediate tumor of cartilage origin. CB involving the sacrum is a very rare pathology. CASE SUMMARY A 17-year-old male with sacral CB was diagnosed as CB during the first surgery, and 18 mo later, the tumor recurred and a second surgery was performed with the same pathology result of CB. CONCLUSION We recommend complete removal of the tumor in a timely manner, provided that surgical conditions are met. At the same time, other diseases should be carefully differentiated in terms of imaging or pathological features so as to avoid erroneous diagnostic conclusions.

show abstract

Chondroblastoma of Thoracic Vertebrae: a Case Report and Review of the Literature

Tabibkhooei

Javadnia

2022

Indian J Surg Oncol

View full text Add to dashboard Cite

Chondroblastoma of thoracic vertebra in young adult causing paraparesis

Cited by 3 publications

References 6 publications

Clinicopathological and Prognostic Characteristics in Spinal Chondroblastomas: A Pooled Analysis of Individual Patient Data From a Single Institute and 27 Studies

Clinicopathological and Prognostic Characteristics in Spinal Chondroblastomas: A Pooled Analysis of Individual Patient Data From a Single Institute and 27 Studies

Sacral chondroblastoma — a rare location, a rare pathology: A case report and review of literature

Chondroblastoma of Thoracic Vertebrae: a Case Report and Review of the Literature

Contact Info

Product

Resources

About