Cholinesterase bei Gestaltungsvorg�ngen in der H�hnerkeimscheibe

Drews, Ulrich; Kussäther, E.; Usadel, K. H.

doi:10.1007/bf00602967

Cited by 11 publications

(2 citation statements)

References 3 publications

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“…Both enzymes have been described in tissues during development (Drews et al 1966;Fluck 1978), and there is evidence for a transient presence of BChE in some embryonic cells where it can sometimes be replaced by ACHE. For instance neuroblasts express BChE before they abruptly accumulate AChE (Layer 19891).…”

Section: Discussionmentioning

confidence: 99%

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Location and activities of acetylcholinesterase and butyrylcholinesterase in the rat and human placenta

et al. 1993

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The location and physiological functions of acetylcholinesterase and butyrylcholinesterase in the placenta are still debated. In the present study the activities of both enzymes were studied histochemically in the rat and human placenta, using an optimized Karnovsky/Roots method. Additionally, they were measured biochemically. Acetylcholinesterase was active in the syncytiotrophoblast, cytotrophoplast cells and the visceral and parietal yolk sac epithelial cells of the rat (n = 10) and in the syncytiotrophoblast, cytotrophoblast cells, endothelial cells and the media of fetal blood vessels of the human placenta (n = 9). Butyrylcholinesterase could not be detected histochemically. Biochemically measured levels at certain developmental stages of the placenta revealed maximum acetylcholinesterase activity in the 8th week p.m. human placentae (102.9 nmol.min-1 per mg protein), 35% lower activity in the 12th week p.m., and minimum (44.1 nmol.min-1 per mg protein) in term placentae. In contrast, maximum butyrylcholinesterase activity was measured in week 12 p.m. (106.9 nmol.min-1 per mg protein). In rat placentae, butyrylcholinesterase activity on gestational day 21 reached 150% of the level on gestational day 16. Acetylcholinesterase activity remained constant. In placentae of pre-eclamptic patients, acetylcholinesterase and butyrylcholinesterase activities were found to be increased by 16% and 45%, respectively. The results suggest that placental acetylcholinesterase can no longer be considered as derived from maternal blood, but is primarily located within rat and human placental tissue.

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Section: Discussionmentioning

confidence: 99%

“…Moreover, it has been suggested that BChE may act as an embryonic AChE in the chicken (Drews 1975) and that these hydrolases take part in morphogenetic processes (Drews et al 1966;Layer 1983). …”

Section: Introductionmentioning

confidence: 99%

Location and activities of acetylcholinesterase and butyrylcholinesterase in the rat and human placenta

et al. 1993

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Patterns of cholinesterase staining during neural crest cell morphogenesis in mouse and chick embryos

Martins‐Green

Erickson

1988

J. Exp. Zool.

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Cholinesterase (ChE) activity has been reported previously in nonneuronal tissues of a variety of avian and mammalian embryos. We report here a comparison study of ChE staining in chick and mouse embryos. Transmission electron microscopy was used to study the distribution of this activity in neuroepithelial, neural crest, somite, and ectodermal cells. Our cytochemical studies show that the distribution of nonspecific ChE staining in these tissues during neurulation is similar in the two species but that acetylcholinesterase (AChE) staining, previously shown to be intense in the chick, is absent in the mouse; the only cells showing the presence of this enzyme at these stages of development in mouse are blood cells. However, AChE staining does appear later in the brain, in neural tissues derived from the neural crest and, perhaps, in some migratory neural crest cells. The differences between AChE distribution in these two species (and that reported previously in the rabbit) indicate that the timing of first appearance of AChE is unrelated to neuroepithelial morphogenesis or to neural crest cell motility. The correlation between nonspecific cholinesterases and morphogenetic movements, however, is supported by these studies.

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Cholinesterase-Aktivit�t im Primitivknoten, in der Schwanzknospe und bei der Chordaentwicklung des H�hnchens

1967

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Cholinesterase bei Gestaltungsvorg�ngen in der H�hnerkeimscheibe

Cited by 11 publications

References 3 publications

Location and activities of acetylcholinesterase and butyrylcholinesterase in the rat and human placenta

Location and activities of acetylcholinesterase and butyrylcholinesterase in the rat and human placenta

Patterns of cholinesterase staining during neural crest cell morphogenesis in mouse and chick embryos

Cholinesterase-Aktivit�t im Primitivknoten, in der Schwanzknospe und bei der Chordaentwicklung des H�hnchens

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