Choline diet improves serum lipid parameters and alters egg composition in breeder ducks

Abstract

Background Choline is an important nutrient, playing key roles in numerous metabolic pathways relevant to animal health. Objectives The objective of this study was to evaluate the effect of dietary choline on the lipid parameters, cardiovascular health (CVH), and levels of egg trimethylamine (TMA) and cholesterol in breeder ducks during the late laying period. Methods A total of 60 Jingjiang ducks were randomly separated into six replicates of 10 ducks each. After peak production until 65 weeks of age, the birds were fed a control basal diet. The same ducks served as the control group until 65 weeks of age, when the same ducks served as the choline‐supplemented group, after 15 days of dietary choline supplementation at 2955 mg/kg choline above and over the basal diet initially provided. The 15 days of choline supplementation included an initial 5‐day acclimatisation period. Results Dietary choline supplementation increased serum TMA (p < 0.01), high‐density lipoprotein cholesterol, very low‐density lipoprotein, and triglyceride levels in older breeder ducks. However, it did not change the levels of trimethylamine N‐oxide but decreased the atherosclerosis index compared with those of the control group (p < 0.01). Moreover, it increased (p < 0.01) the egg yolk TMA levels but did not change the concentrations of cholesterol in egg yolk. Conclusions Dietary choline supplementation had a beneficial effect on lipid parameters and CVH in older breeder ducks, although it increased the serum and egg yolk TMA levels.

Nutrición animal: Texto de formación universitaria

“…La colina suplementaria en la dieta tuvo un efecto beneficioso sobre los parámetros lipídicos y la salud cardiovascular de los patos reproductores, ya que aumentó los niveles séricos de HDL-C y disminuyó el índice de ateroesclerosis, un predictor del riesgo de enfermedad cardiovascular en patos. Aunque aumentó los niveles de trimetilamina en la yema de huevo en patos, no alteró la concentración de colesterol en la yema de huevo, evidenciado que la suplementación con colina en la dieta mejora los parámetros de lípidos y salud cardiovascular en patos (Song et al, 2022).…”

Dietary Methionine Restriction Promotes Fat Browning and Attenuates Hepatic Lipid Accumulation in High-Choline-Fed Mice Associated with the Improvement of Thyroid Function

“…Population-level assessments of dietary consumption of choline showed that choline intake varies approximately 4 times or higher. , Numerous studies have shown that high-choline diets (HCD) caused an increase in oxidative stress and inflammation levels as well as promoted dyslipidemia and lipid accumulation, − and increased the risk of atherosclerotic cardiovascular disease (CVD). − Moreover, previous studies had found that thyroid lesions had notably elevated choline levels than healthy adjacent thyroid tissue, and choline has often been proposed as a thyroid cancer biomarker . A recently published study showed that the choline-supplemented diet decreased triiodothyronine (T3) and thyroxine (T4) levels in the serum of ducks . Thyroid hormones (TH) are synthesized and released by the thyroid gland and are involved in lipid metabolism.…”

“…17 A recently published study showed that the choline-supplemented diet decreased triiodothyronine (T3) and thyroxine (T4) levels in the serum of ducks. 18 Thyroid hormones (TH) are synthesized and released by the thyroid gland and are involved in lipid metabolism. Thus, they are consequently highly associated with lipid accumulation.…”