Choline chloride–thiourea, a deep eutectic solvent for the production of chitin nanofibers

Potential applications of deep eutectic solvents in nanotechnology

“…A few studies reported the successful recycling of DESs after using them as media to disperse and produce nanoparticles and nanocomposites [52,58,64,85,86]. …”

Improving agar electrospinnability with choline-based deep eutectic solvents

“…In any case, the growing interest in natural fibers made from ILs for biomedical applications [20] seem encouraging. Finally, the advantages pointed out to DESs when compared to conventional ILs [22,23] make their applicability in the electrospinning of natural polymers very promising [8,19,20]. Moreover, these eutectics can be recycled and reused with similar efficiency to unprocessed DESs [23].…”

“…Particular emphasis has been given to DESs derived from the quaternary ammonium salt (2-hydroxyethyl)trimethylammonium chloride (choline chloride, ChCl), due to its very low cost, biodegradability, non-toxicity as well as renewable nature [21,22]. Very recently, Mukesh et al produced chitin nanofibers by sonication using a DES based on ChCl and thiourea [23]. A eutectic mixture with a freezing point of 12 • C is also formed when mixing ChCl (melting point, m.p.…”

Chitin, Chitosan, and Silk Fibroin Electrospun Nanofibrous Scaffolds: A Prospective Approach for Regenerative Medicine

“…1-butyl-3-methylimidazolium hydrogen sulfate and 1-methylimidazolium hydrogen sulfate and with choline-based ionic liquids, choline hydrogen sulfate, and choline acrylate. Authors concluded that chitin nanofibers obtained by using deep eutectic solvents show greater elasticity than calcium alginate bio-nanocomposite gel beads, and hence used the prepared matrix to observe the release profile of anticancer drug 5-fluorouracil and found that it gives very slow release which may be very beneficial in chemotherapy [80].…”