Cholesterol embolization syndrome following thrombolysis during acute myocardial infarction

Abstract

Cholesterol embolizations from the aorta are difficult to treat and may end in renal failure. Since treatment options are limited without proven efficacy, increased awareness by the clinicians is needed.

Cholesterol Atheroembolism Syndrome: Current State of the Problem

“…Ранее указывалось на участие антикоагулянтов и фибринолитиков в развитии СХАЭ. Считается, что эти лекарственные средства приводят к разрыву атеросклеротических бляшек, вызывая внутреннее кровоизлияние и нарушение фиброзных капсул [9]. Однако, самостоятельно в отсутствие внутрисосудистых вмешательств или операций, эти препараты редко приводят к развитию СХАЭ [10,11].…”

Acute onset of severe livedo reticularis in a patient with myocardial infarction

“…Interestingly, the kidney and skin are the most commonly affected organs. Renal failure and cutaneous manifestations such as livedo reticularis, blue toe syndrome, ulcers, purpura and digital gangrene are common signs [ 2 ]. Skin lesions can be the only clinical presentation, although embolization syndrome has the potential to cause multi-organ involvement of the brain, eyes, gastrointestinal tract and kidneys.…”

“…Usually, patients have unstable atherosclerotic lesions over the entire aorta. Male gender, advanced age, acute coronary syndrome, multivessel coronary artery disease, hypertension, smoking, cerebrovascular disease and aortic aneurysm have been recognized as major risk factors for embolization syndrome [ 2 ]. In our patient, risk factors such as male gender, acute coronary syndrome and active smoking were present.…”