Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa

Mercan, Erdinc; Duman, Uğur; Tıhan, Deniz; Dilektaşlı, Evren; Şenol, Kazım

doi:10.1186/s40064-016-3641-z

Cited by 24 publications

(24 citation statements)

References 21 publications

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“…Studies have reported that H. pylori gastritis is seen equally in both genders because of the same probability of being affected by H. pylori infection, but DGR may be more common in women due to functional pathophysiology [19]. Mercan et al reported that there was no significant gender difference between groups with and without DGR [22]. The results obtained from our study support this finding.…”

Section: Discussionsupporting

confidence: 87%

The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density of Helicobacter pylori and on Gastritis in Childhood

Ağın

Kayar²

2019

Medicina

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Background and Objectives: Although there are many studies that investigate the relationship between duodenogastric reflux (DGR) and Helicobacter pylori in adult patients, the reported data are contradictory. In addition, there are very few studies in the literature investigating the relationship between DGR and H. pylori in the pediatric age group. In the present study, we investigated the effect of primary DGR on H. pylori and gastritis. Materials and Methods: A total of 361 patients who were referred to the clinic of our hospital with dyspeptic complaints who had an upper gastrointestinal system endoscopy and a gastric biopsy were included in the study. Results: DGR was detected in 45 cases, and 316 cases that did not have DGR were considered as the control group. Comparisons were made between the DGR cases and the control group in terms of risk factors (age, gender), the presence and density of H. pylori, and the presence and severity of gastritis. The average age of the patients who were included in the study was 11.6 ± 4.6 years. A total of 128 (36%) of the cases were male and 233 (64%) were female. DGR was present in 45 (13%) of the cases. The average age of the patients with DGR was 13.9 ± 3.1 years, the average age of the control group was 11.3 ± 4.7, and there were statistically significant differences (p < 0.001). No significant differences were detected in terms of gender between DGR and the control group (p > 0.05). H. pylori (+) was detected in 29 (64%) of patients with DGR, and in 202 (64%) of the control group. No significant differences were detected between H. pylori prevalence (p = 0.947). Gastritis was detected in 37 (82%) of the patients with DGR, and in 245 (77%) of the control group (p = 0.476). No significant differences were detected between the presence and density of H. pylori, gastritis presence, severity and DGR (p > 0.05). Conclusions: The ages of patients with DGR were significantly higher than in the control group, and advanced age was shown to be a risk factor for primary DGR. It was found that the presence of DGR has no effect on the presence and severity of H. pylori. Given this situation, we consider it is important to eradicate H. pylori infection, especially in the case where H. pylori is present together with DGR.

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Section: Discussionsupporting

confidence: 87%

The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density of Helicobacter pylori and on Gastritis in Childhood

Ağın

Kayar²

2019

Medicina

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“… 25 Hyperglycemia can reduce gastric acid secretion by inhibiting the vagal cholinergic pathways, 7 , 8 and a recent previous study identified cholecystectomy as a cause of the severe duodenogastric reflux strongly associated with early gastric mucosal changes. 26 The high osmotic pressure induced by i.v. dextrose also can reduce gastrointestinal wall contractions.…”

Section: Discussionmentioning

confidence: 99%

Does perioperative intravenous dextrose reduce postoperative nausea and vomiting? A systematic review and meta-analysis

Kim¹,

Kim²,

Kim³

et al. 2018

TCRM

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PurposePerioperative dextrose-containing fluid administration has been used as a non-pharmacologic preventive measure against postoperative nausea and vomiting (PONV), a common and distressing complication of anesthesia. However, its efficacy remains unclear as previous studies reported inconsistent results. Our objective was to compare dextrose-containing fluid with non-dextrose-containing fluid in terms of PONV for 24 hours after surgery under general anesthesia. The effects of dextrose according to different types of surgery and the fluid volume were also examined.MethodsWe performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing dextrose-containing fluid with non-dextrose-containing fluids after general anesthesia in terms of PONV incidence and the need for rescue anti-emetic therapies for 24 hours after surgery. A literature search was performed, using Medline, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, and Scopus, up to February 2018.ResultsWe included seven RCTs. Compared with the control group, perioperative dextrose administration did not reduce the risk for PONV, with a relative risk (RR) of 0.72 (95% CI: 0.50–1.03). However, perioperative dextrose reduced the requirement for anti-emetics, compared with the control group, with a RR of 0.60 (95% CI: 0.44–0.83). The quality of evidence in this meta-analysis was poor due to high risks of selection and performance biases and substantial statistical heterogeneity. After subgroup analysis, the risk for PONV was reduced in patients who had undergone laparoscopic cholecystectomy, but not other surgeries, and the effects of dextrose on the risk for PONV did not differ according to the fluid volume administered.ConclusionPerioperative intravenous (i.v.) dextrose did not reduce the risk for PONV. However, it did reduce the need for anti-emetics after general anesthesia. Furthermore, the effects of dextrose varied according to the surgery type. Further studies are needed to determine the benefits of perioperative i.v. dextrose administration as a preventive measure against PONV.

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“…13 En México en 2016 se realizó un estudio con 345 pacientes que padecían síndrome de colon irritable con el subtipo de predominancia de diarrea, en el cual se describió que la prevalencia de dicho síndrome en pacientes colecistectomizados fue 3.6 veces mayor. 27 Por otro lado, la incidencia de gastritis diagnosticada por endoscopia por dolor crónico postcolecistectomía también se ha descrito antes, 28 se considera a la colecistectomía como un riesgo significativo para la gastritis biliar, 29 causante de reflujo y cambios en la mucosa gástrica, 30 incluso se ha supuesto tratamiento con ácido ursodesoxicólico en el tratamiento para la gastritis por reflujo alcalino postcolecistectomía con efectos positivos. 31 De hecho, se ha sugerido que en pacientes que serán sometidos a una colecistectomía deba realizarse una endoscopia preoperatoria, ya que en 28.8% de los casos existen cambios endoscópicos que expliquen el dolor abdominal, 32 los diagnósticos más frecuentes causantes del síndrome postcolecistectomía son úlceras pépticas y hernias hiatales.…”

Section: Wwwmedigraphicorgmxunclassified

Incidencia del síndrome postcolecistectomía en pacientes adultos

López¹,

Alberti‐Minutti²,

Trujillo³

2021

Acta Médica Grupo Ángeles

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La colecistectomía laparoscópica (CL) es el tratamiento ideal para la colelitiasis, pero la persistencia de síntomas postoperatorios es frecuente, a éstos se les conoce como síndrome postcolecistectomía (SPC) y está poco reportado en México, por lo que el objetivo del estudio es determinar su incidencia. Material y métodos: Estudio observacional transversal. Se analizaron 220 expedientes clínicos de pacientes colecistectomizados en 2017, en el Hospital Nuevo Sanatorio Durango. Se evaluaron los cinco síntomas más frecuentes: dolor abdominal en cuadrantes superiores, náusea, vómito, diarrea y distensión abdominal, prequirúrgicamente y a un año de la cirugía. Resultados: El SPC se presentó en 23.1% (n = 36), los síntomas persistentes fueron: distensión abdominal (21.8%), dolor (14.7%), náusea (5.8%), diarrea (4.5%) y vómito (0.6%). Los pacientes con dolor abdominal de tipo biliar, náuseas y vómito redujeron significativamente al año de la cirugía. La cirugía no modificó el riesgo de presentar diarrea y fue un factor de riesgo para presentar distensión abdominal (OR 2.08). Diez pacientes no tuvieron un diagnóstico certero como causa del SPC (32.3%). Conclusión: El SPC se presenta frecuentemente, debe evaluarse de manera correcta y descartar complicaciones postquirúrgicas. Se ha relacionado una mayor incidencia de síndrome de colon irritable tras una CL.

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Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa

Cited by 24 publications

References 21 publications

The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density of Helicobacter pylori and on Gastritis in Childhood

The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density of Helicobacter pylori and on Gastritis in Childhood

Does perioperative intravenous dextrose reduce postoperative nausea and vomiting? A systematic review and meta-analysis

Incidencia del síndrome postcolecistectomía en pacientes adultos

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