Chlorhexidine for the Treatment of Peri-Implantitis: Is it a Benison?

Surgical management of peri-implantitis in adjunction with BlueM oxygen therapy: a case report with 5-years follow-up

“…6,15 Several conventional anti-infective modalities have been employed to treat peri-implantitis. 7,16 For instance, ultrasonic scaling with titanium tip is commonly used to clean the infected implant surface. As shown in our case report, the treatment protocol was preceded by mechanical (ultrasonic) debridement of the implant surface.…”

“…5,6 Although chlorhexidine is widely used in the treatment of peri-implantitis, there is an increase awareness of its side effects on bone cells as well as on the surface topography of dental implants. 7 Chlorhexidine can cause cell cytotoxicity, in turn, can hinder the potential of bone healing around implants. Therefore, it can be recommended to discourage chlorhexidine for treating peri-implantitis cases.…”

“…Therefore, it can be recommended to discourage chlorhexidine for treating peri-implantitis cases. 7 Recently, an oxygenating product, known as BlueM oxygen gel, has been developed by Dr. Peter Blijdorp and co-workers. 8,9 The BlueM formula is formed by chemical complexation of sodium perborate with specific carriers such as glycerol and cellulose, which provides controlled and slow release of oxygen.…”

From manufacturers to clinicians, the release of dental implant particles can no longer be ignored

“…The most common feasible causes of Ti particle release are friction during implant placement procedures, implant surface corrosion, and fretting phenomena at the implant‐abutment interphase 29 . The use of dental hygiene products and antiseptic agents such as fluoride and chlorhexidine have been linked with alterations to the implant surface topography and increased corrosion 30,31 . In addition, implant debridement procedures, for example, surface cleaning with mechanical and/or chemical means, used during implant maintenances and treatment of peri‐implantitis, such as implantoplasty, were also reported to be the causes of particle release 25,32 .…”

“…29 The use of dental hygiene products and antiseptic agents such as fluoride and chlorhexidine have been linked with alterations to the implant surface topography and increased corrosion. 30,31 In addition, implant debridement procedures, for example, surface cleaning with mechanical and/or chemical means, used during implant maintenances and treatment of peri-implantitis, such as implantoplasty, were also reported to be the causes of particle release. 25,32 Authors' own ex vivo study has found that the amount of metallic particle and ion release during placement was dependent on both implant material and design, where grade 5 titanium alloy (Ti-6AL-4V) implants resulted in more release compared to commercial pure (grade 4) or Roxolid ® (Ti-15Zr, a Ti alloy composed of 15% zirconium) implants.…”