SummaryMastication as we all know has always been related to its primary function of digestion, but little do we know that it produces an enhancing effect on general health, especially the cognitive performance related aspects of memory. Recent studies have shown its association with activation of various brain regions, however little is known about its effects on neuronal activity in these specified regions. According to the enormous evidences collected so far, mastication has proved to be effective in conducting huge amount of sensory information to the brain, and maintaining learning and memory functions of hippocampus. Therefore it is essential that we maintain normal occlusion and preserve the masticatory function as long as possible to prevent the attenuation of hippocampus, caused by occlusal disharmony and reduced mastication. We provide an overview on how mastication activates various cortical areas of the brain and how an increase in the cerebral blood oxygen level of hippocampus and prefrontal cortex (PFC) accentuates the learning and memory process. We also justify why maintaining and establishing a normal occlusion is important from neurological point of view.
Aim:
This study aims to test the tensile strength and growth of
Candida albicans
on Viscogel tissue conditioner when incorporated with coconut oil (CCO) and to compare its efficacy with other antifungal agents.
Settings and Design:
Evaluative -
In-vitro
study design.
Materials and Methods:
Fifty dumbbell-shaped samples (
n
= 10) of Viscogel tissue conditioner were fabricated according to ASTM standard and were classified into 5 groups (10% CCO, 30% w/w tea tree oil, 5% w/w fluconazole, 0.03% w/w silver nanoparticles, and plain tissue conditioner). These samples were compared and evaluated for their tensile strength. Further to test the antifungal activity, a total of 60 samples (
n
= 15) were fabricated, each group (
n
= 15) was further divided into three subgroups (
n
= 5), namely 24-h, 3-day, and 5-day period, which were inoculated in sabouraud dextrose agar plate to test for the growth of
C. albicans
.
Statistical Analysis Used:
Oneway ANOVA and
post hoc
Tukey honestly significant difference test.
Results:
10% w/w CCO yielded a mean tensile strength of 20.06 as compared to the plain tissue conditioner which showed a mean tensile strength of 17.81. Similarly, 10% w/w CCO incorporated into Viscogel tissue conditioner showed a significant reduction in the colonization of
C. albicans
on the 5
th
day.
Conclusions:
10% w/w of CCO when mixed with Viscogel tissue conditioner showed a significant reduction in the growth of
C. albicans
, and addition of the same increased the tensile strength of the tissue conditioner.
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