1979
DOI: 10.1128/aac.16.6.855
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Chlorhexidine as an effective agent against Chlamydia trachomatis in vitro and in vivo

Abstract: In a small field trial, chlorhexidine (50 micrograms/ml) was as effective against clinical trachoma as topical tetracyclines or oral co-trimoxazole; in vitro, 2.5 micrograms/ml was chlamydicidal.

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Cited by 10 publications
(3 citation statements)
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“…Chlorhexidine is well known to be effective against a range of Gram positive and Gram negative bacteria, is being used for the treatment of Acanthamoeba keratitis,10 11 and was also thought from one study to be effective against Chlamydia trachomatis. 12 Chlorhexidine digluconate is already used as a preservative in eye preparations and is therefore approved for use in low concentrations in the human eye. It has been used in several other clinical situations for about 40 years.…”
Section: Discussionmentioning
confidence: 99%
“…Chlorhexidine is well known to be effective against a range of Gram positive and Gram negative bacteria, is being used for the treatment of Acanthamoeba keratitis,10 11 and was also thought from one study to be effective against Chlamydia trachomatis. 12 Chlorhexidine digluconate is already used as a preservative in eye preparations and is therefore approved for use in low concentrations in the human eye. It has been used in several other clinical situations for about 40 years.…”
Section: Discussionmentioning
confidence: 99%
“…In the mid‐1970s, longitudinal studies on the prevalence and treatment of trachoma were conducted in a group of communities in the Katherine region by a team lead by one of us (PS) (as a District Medical Officer in the Northern Territory. [The team included members from the University of Melbourne (DG) and the Royal Victorian Eye and Ear Hospital] 7 . Further studies on trachoma were conducted in one of the same communities in 2007 8 …”
Section: Introductionmentioning
confidence: 99%
“…[The team included members from the University of Melbourne (DG) and the Royal Victorian Eye and Ear Hospital]. 7 Further studies on trachoma were conducted in one of the same communities in 2007. 8 We were able to obtain baseline images of the everted upper eyelids obtained during these two studies, and this paper presents the prevalence and severity of active trachoma in children in this community at those two time points.…”
Section: Introductionmentioning
confidence: 99%