Chlamydia pneumoniae sp. nov. for Chlamydia sp. Strain TWAR

Abstract

A third species, Chlamydia pneumoniae, is proposed for the genus chlamydia. This bacterium is a human respiratory pathogen, which has been referred to as the TWAR strain of Chlamydia. Species identification is based on ultrastructural differences in the elementary bodies, deoxyribonucleic acid analysis, and serology.

Amplification of plasmid and chromosome chlamydia dna in synovial fluid of patients with reactive arthritis and undifferentiated seronegative oligoarthropathies

“…It has long been known that chlamydial cell walls, especially those of the elementary bodies, are highly resistant to various environmental conditions and intracellular degradation (39,40). The possibility that we were detecting sequences of Chlamydia pneumoniae cannot be excluded but is unlikely, since our systems 1 and 2 were targeted to the plasmid DNA, and the isolates of C pneumoniae examined to date contain no extrachromosomal DNA (41,42). Only 1 control SF sample, from a patient with mechanical arthropathy, was found to be positive for C trachomatis DNA after amplification.…”

Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination

“…Additional evidence for the presence of C. pneumoniae among different population groups was reported using a method that enables the detection of specifi c reactions without the interference of cross reactions among the different species of Chlamydia (23) (24) . Laboratory diagnosis of chlamydial infections…”

The Role of Chlamydophila (Chlamydia) Pneumoniae in the Pathogenesis of Coronary Artery Disease

“…It was first named Chlamydia TWAR (for Taiwan Acute Respiratory), when close resemblance was found between bacteria isolated in patients from Taiwan and those www.intechopen.com Chlamydia 158 treated for acute respiratory failure in the USA (Grayston et al, 1986). The new strain was later found to be significantly different from the already known Chlamydia trachomatis and Chlamydia pisttaci, and was named Chlamydia pneumoniae (Grayston et al, 1989). The name was later officially changed to the one used at present, namely Chlamydophila pneumoniae.…”