“…Indeed, induction of CDK1 has been linked to the growth of human colorectal cancer and acute myeloid leukemia [33–34]; the reduction of p27 has been liked to the genesis and progression of a broad array of human cancers, including cancers of the breast, colon, prostate, ovary, lung, stomach, and others [35–37]. The increase of NSun2 levels observed in a variety of human cancers, including those originating in the colon, esophagus, stomach, liver, oral cavity, pancreas, uterus, cervix, prostate, kidney, bladder, thyroid, breast, and skin [25, 38], may be part of a program of senescence repression involving reduced levels of p27.…”