Chitosan (PEO)/bioactive glass hybrid nanofibers for bone tissue engineering

Talebian, Sepehr; Mehrali, Mehdi; Mohan, Saktiswaren; Raghavendran, Hanumantha Rao Balaji; Mehrali, Mohammad; Khanlou, Hossein Mohammad; Kamarul, Tunku; Afifi, Amalina M.; Abass, Azlina Amir

doi:10.1039/c4ra06761d

Cited by 62 publications

(25 citation statements)

References 43 publications

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“…95,96 They are biodegradable and favorable to biomineralization and compatible with osteoblast cells. However, their brittle nature is an issue for their mechanical strength that needs to be improved.…”

Section: Bone Regenerationmentioning

confidence: 99%

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

2016

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Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be applied to a broad range of resorbable medical devices. In particular, poly(trimethylene carbonate) (PTMC), its copolymers, and its derivatives are currently studied due to their unique degradation characteristics that are different from those of aliphatic polyesters. Furthermore, their flexible and hydrophobic nature has driven the application of PTMC-based polymers to soft tissue regeneration and drug delivery. This review presents the diverse applications and functionalization strategies of PTMC-based materials in relation to recent advances in medical technologies and their subsequent needs in clinical settings.

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Section: Bone Regenerationmentioning

confidence: 99%

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

2016

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“…Also, from EDX analysis results, the presence of Si, Ca and P indicating that BG was conducted to chitosan matrix. The bonebonding capability of a composite is determined by its ability to formation of apatite layer on its surface upon immersion in SBF solution for (33 day), a part from some exception where as it is possible to a material to be directly bonded to living bone without the formation of apatite on their surface [25].…”

Section: Morphological Analysis Of Samples (Sem and Edx)mentioning

confidence: 99%

Preparation of Bioglass/Chitosan Composite incorporated with Dexamethasone by Sol-gel Method.

Raboh

El-khooly

Hassaan

2019

Egypt. J. Biophys. Biomed. Engng.

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“…Moreover, in order to produce a roughened surface with proper morphology, manufacturers have utilized the acid etching methods as a sequential method after sandblasting. The capacity of acidic surfaces in making chemical bonding, increasing osseointegration and enhancing biocompatibility has been widely illustrated [21][22][23][24]. Furthermore, the type and concentration of acid has been identified as an important key in investigating the rate of texturing and roughening of titanium surfaces [25,26].…”

Section: Introductionmentioning

confidence: 99%

Prediction and characterization of surface roughness using sandblasting and acid etching process on new non-toxic titanium biomaterial: adaptive-network-based fuzzy inference System

Khanlou

Ang

Barzani

et al. 2015

Neural Comput & Applic

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An adaptive neuro-fuzzy system (ANFIS) model was employed to predict the surface roughness. Surface roughening of titanium biomaterials has a crucial effect on increasing the biocompatibility. For this purpose, sandblasted, large-grit, acid-etched (SLA) has been introduced as an effective method to change the surface texturing and roughness. Subsequent processes-polishing, sandblasting and acid etching or SLA-were employed to modify the surface. Alumina particles for surface blasting and Kroll's etchant (3 ml HF ? 6 ml HNO 3 ? 100 ml H 2 O) for acid etching were utilized in this experiment. This was performed for three different periods of time (10, 20 and 30 s) and temperatures (25, 45 and 60 centigrade). Correspondingly, the Ti-13Zr-13Nb surfaces were evaluated using a field emission scanning electron microscope for texturing, contact mode profile meter for the average surface roughness (Ra) (nm) and atomic force microscopy for surface texturing at the nano-scale. In addition, the surface roughness was reduced in each condition, particularly in extremely high conditions. Significantly, the ANFIS model predicted the Ra amount of textured surface with an error band of 10 %. This research presents an idea to use the ANFIS model to obtain proper biological signs on the roughened surface in terms of surface roughness.

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Chitosan (PEO)/bioactive glass hybrid nanofibers for bone tissue engineering

Abstract: Incorporation of bioactive glass into chitosan (PEO) nanofibers leads to improvement of strength and bone-cell differentiation capability.

Cited by 62 publications

References 43 publications

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

Preparation of Bioglass/Chitosan Composite incorporated with Dexamethasone by Sol-gel Method.

Prediction and characterization of surface roughness using sandblasting and acid etching process on new non-toxic titanium biomaterial: adaptive-network-based fuzzy inference System

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