Chitosan encapsulated quantum dots platform for leukemia detection

Sharma, Aditya; Pandey, Chandra Mouli; Sumana, Gajjala; Soni, Udit; Sapra, Sameer; Srivastava, Avanish Kumar; Chatterjee, Tushar; Malhotra, Bansi D.

doi:10.1016/j.bios.2012.05.010

Cited by 68 publications

(44 citation statements)

References 34 publications

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“…Malhotra et al [22] deposited the positive chitosan encapsulated CdTe QDs onto the indium-tin-oxide (ITO) coated glass substrates via electrophoretic deposition (EPD) technique, and the prepared nanostructure composite was found to detect target DNA in a wide concentration range. Additionally, the fabricated DNA biosensor could distinguish clinical samples of chronic myelogenous leukemia (CML) positive and negative patients.…”

Section: Introductionmentioning

confidence: 99%

The fluorescent interactions between amphiphilic chitosan derivatives and water-soluble quantum dots

Fei

Zhang

et al. 2016

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Section: Introductionmentioning

confidence: 99%

The fluorescent interactions between amphiphilic chitosan derivatives and water-soluble quantum dots

Fei

Zhang

et al. 2016

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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“…2B) was employed to further characterize the modification in the whole process. Compared to pure MBs in gel lane (1), the ligation between MBs and targets formed a sharp band with larger molecular weight in lane (2). The lower band in lane (3) matched with the band in lane (2), and the upper band belonged to DNA duplex engendered in CSRP, indicating the successful circular strand replacement.…”

Section: Resultsmentioning

confidence: 83%

“…BCR/ABL fusion gene, the reciprocal translocation between chromosomes 9 and 22, plays a pivotal role in the pathogenesis of chronic myeloid leukemia (CML) [1]. Some methods such as blot hybridization, flow cytometry [2], fluorescence in situ hybridization [3], and real-time quantitative reverse transcription PCR [4] have been established for fusion gene detection.…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive electrochemical detection of BCR/ABL fusion gene fragment based on polymerase assisted multiplication coupling with quantum dot tagging

Tan

Chen

et al. 2013

Electrochemistry Communications

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“…Extreme PCR shortens traditional PCR cycle time [26]. And the quantum chemistry method is proved to detect very low concentrations of DNA template (2.56 pm) [27].…”

Section: Prospective Methodsmentioning

confidence: 99%

A review of the challenge in measuring and standardizing BCR-ABL1

Cui

et al. 2017

Clinical Chemistry and Laboratory Medicine (CCLM)

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Breakpoint cluster region-Abelson (BCR-ABL1) translocation is the characteristic sign of chronic myeloid leukemia (CML). The quantitation of BCR-ABL1 messenger RNA is requisite for patients with CML, and reverse-transcription real-time quantitative polymerase chain reaction (RQ-PCR) is the method used most extensively in testing laboratories worldwide. Nevertheless, substantial variation in RQ-PCR results from different laboratories makes interlaboratory comparability inconvincible owing to the lack of standardization. To facilitate interlaboratory comparative assessment and international standardization, an international scale (IS) for BCR-ABL1 was proposed. The laboratory-specific conversion factors derived from the IS can convert local different values to the IS without changing procedures. The standardization of BCR-ABL1 also includes the whole analytical process, so it is noteworthy to pay attention to the quality control before BCR-ABL1 quantitative analysis. More importantly, the World Health Organization has validated a first genetic reference panel which is limited to the manufacturers to produce and calibrate secondary reference reagents. Also, a certified reference plasmid, ERM-AD623, was internationally accepted. This article mainly focuses on BCR-ABL1 measurement and these standardization efforts in progress.

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Chitosan encapsulated quantum dots platform for leukemia detection

Cited by 68 publications

References 34 publications

The fluorescent interactions between amphiphilic chitosan derivatives and water-soluble quantum dots

The fluorescent interactions between amphiphilic chitosan derivatives and water-soluble quantum dots

Ultrasensitive electrochemical detection of BCR/ABL fusion gene fragment based on polymerase assisted multiplication coupling with quantum dot tagging

A review of the challenge in measuring and standardizing BCR-ABL1

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