Chitosan/collagen blends with inorganic and organic additive—A review

Abstract

This review provides a report on recent studies of composite materials based on a chitosan and collagen mixture due to their biocompatibility and bioactivity. Those natural polymers are most widely used to obtain biomaterials. However, the materials based on chitosan/collagen complexes present poor mechanical parameters, as well as high swelling behavior and enzymatic degradation rate. Such properties are considered problematic for the material clinical application. An increased interest in composite materials has been observed due to their enhanced physicochemical properties. A composite material preparation involves different compounds addition to natural polymers. Herein, the use of organic and inorganic additives has been reported. Moreover, the potential application of composite materials based on chitosan/ collagen complexes in the tissue engineering science has been discussed. K E Y W O R D Schitosan, collagen, composite materials, tissue engineering How to cite this article: Kaczmarek B, Sionkowska A. Chitosan/collagen blends with inorganic and organic additive-A review. Adv Polym Technol.

Marine Spongia collagens: Protein characterization and evaluation of hydrogel films

“…The objective of the present work was to investigate the protein profile of isolated collagens from these Spongia species and to evaluate the physicochemical characteristics of hydrogel films based on Spongia collagens, with and without addition of auxiliary crosslinkers or chitosan. There are reports of using chitosan to enhance some key properties such as mechanical and biological functionalities of biomaterials based on collagen of marine fish and bovine sources . Composite materials were developed for bone tissue engineering based on marine sponge species .…”

“…There are reports of using chitosan to enhance some key properties such as mechanical and biological functionalities of biomaterials based on collagen of marine fish and bovine sources. [29][30][31][32] Composite materials were developed for bone tissue engineering based on marine sponge species. 22,24 This is the first report of investigation of protein profile of Spongia officialis collagen and processing of the hydrogel films in conjunction with chitosan.…”

Preparation and characterization of biomedical collagen–chitosan scaffolds with entrapped ibuprofen and silver nanoparticles

“…These materials are of special interest for treatment of skin damage, particularly for wounds and burns . The three‐dimensional (3D) porous architecture, hydrophilic nature, high sorption properties, mechanical strength, and good adhesion make collagen–chitosan scaffolds prospective candidates as carriers of drugs for targeted release .…”

Magnetic chitosan functionalized with β‐cyclodextrin as ultrasound‐assisted extraction adsorbents for the removal of methyl orange in wastewater coupled with high‐performance liquid chromatography

“…Natural polymers composed of adsorbents have been utilized widely , and among them chitosan (CT) together with its derivatives as polysaccharides has received considerable attention . With important structural and biological properties, CT has been widely applied in many fields . The combination of CT with magnetic cores gives the features of both the magnetic cores (ease of magnetic separation) and CT (surface functionalization) .…”

“…Natural polymers composed of adsorbents have been utilized widely [1][2][3][4][5][6], and among them chitosan (CT) together with its derivatives as polysaccharides has received considerable attention [7,8]. With important structural and biological properties, CT has been widely applied in many fields [9]. The combination of CT with magnetic cores gives the features of both the magnetic cores (ease of magnetic separation) and CT Article Related Abbreviations: ChCl, choline chloride; CM-β-CD, carboxymethyl-β-cyclodextrin; CT, chitosan; DES, deep eutectic solvent; MCT, magnetic chitosan; MO, methyl orange; β-CD, β-cyclodextrin (surface functionalization) [10].…”