Chitosan–cellulose composite membrane for affinity purification of biopolymers and immunoadsorption

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

“…Yang et al [95] reported that the tensile strength of the composite cellulose membranes coated with different chitosan concentrations increased with increasing chitosan concentration.…”

“…For the obtained materials such parameters as the degree of quaternization and/or the degree of substitution should be determined and their influence on the investigated biological properties tested, -the biological properties of chitin/chitosan materials used directly in biomedical applications (e.g., antimicrobial effects) could be different that observed for materials obtained after preparation of nanoparticles, microspheres, hydrogels, films, fibers or tablets, -considerable research efforts should be directed towards developing safe and efficient chitin/chitosan-based formulations. As an example, such factors as particle size requirement, the thermal and chemical stability of the active agent, reproducibility of the kinetic release profiles, stability of the final product and residual toxicity associated with the final product depends upon the methods of preparing chitosan-based micro/nanoparticulate drug delivery systems, -the influence of physicochemical properties apart from M W and DA on chitosan-based formulation affecting the delivery of DNA and siRNA [51] and on antimicrobial properties of chitin/chitosan materials [68][69][70][71][72][73][74][85][86][87][88]94,95,104,105] is the best known. For other biological properties our knowledge is still not sufficient, -chitin/chitosan properties are interrelated and many times they could influence the bioactivity in a conflicting manner, e.g., would healing properties and permeation enhancement properties are inevitably linked to other such as mucoadhesion and cytotoxicity.…”

Enhanced Separation Performance of Cellulose Acetate Membrane For Brackish Water Separation Using Modification of Additives and Thermal Annealing

“…For certain purposes, additives are often added to the dope solution. Kind of additive that is often used is polyethylene glycol (PEG).The manufacture of membranes with addition of PEG additive has the effect of increasing rate membrane permeation because PEG is known as a pore-forming organic material on the membrane [5][6][7]. Increasing amout of PEG can increase the porosity of the chitosan-cellulose composite membrane, which is shown through an increase in flux of the membrane [6][7][8].…”

“…Increasing amout of PEG can increase the porosity of the chitosan-cellulose composite membrane, which is shown through an increase in flux of the membrane [6][7][8]. PEG is a biocompatible compound, highly hydrophilic and anti-fouling [6].…”

Drug Delivery System Using Biodegradable Nanoparticles Carrier

“…Chitosan has various useful characteristics including high chemical resistance, big thermal stability, affinity with dyes and metal ions, and bio-compatibility. Over the last 20 years, these kinds of characteristics have been widely applied to chemical engineering, biomedicine, waste water treatment, the collection and recycling of metal, functional membranes, and the controlling of metal ions in a body [28][29][30][31][32][33]. As chitosan dissolves in an acidic solution, has reactive amino suitable for chemical changes, and is harmless to people, the functional polymer made from chitosan can be an excellent ion exchange resin or an absorbent.…”